Abstract：
The aim of this study was to determine the relationship between short-term exposure to ambient air pollution and the number of daily hospital admissions for genitourinary disorders in Lanzhou. Hospital admission data and air pollutants, including PM2.5, PM10, SO2, NO2, O38h and CO, were obtained from the period 2013 to 2020. A generalized additive model (GAM) combined with distribution lag nonlinear model (DLNM) based on quasi-Poisson distribution was used by the controlling for trends, weather, weekdays and holidays. Short-term exposure to PM2.5, NO2 and CO increased the risk of genitourinary disorder admissions with RR of 1.0096 (95% CI 1.0002-1.0190), 1.0255 (95% CI 1.0123-1.0389) and 1.0686 (95% CI 1.0083-1.1326), respectively. PM10, O38h and SO2 have no significant effect on genitourinary disorders. PM2.5 and NO2 are more strongly correlated in female and ≥ 65 years patients. CO is more strongly correlated in male and < 65 years patients. PM2.5, NO2 and CO are risk factors for genitourinary morbidity, and public health interventions should be strengthened to protect vulnerable populations.
摘要：
这项研究的目的是确定短期暴露于环境空气污染与兰州泌尿生殖系统疾病每日住院人数之间的关系。入院数据和空气污染物，包括PM2.5、PM10、SO2、NO2、O38h和CO，从2013年到2020年获得。将基于拟泊松分布的分布滞后非线性模型(DLNM)与广义加性模型(GAM)相结合用于趋势控制。天气,工作日和节假日。短期暴露于PM2.5，NO2和CO会增加泌尿生殖系统疾病入院的风险，RR为1.0096（95％CI1.0002-1.0190），1.0255（95%CI1.0123-1.0389）和1.0686（95%CI1.0083-1.1326），分别。PM10、O38h和SO2对泌尿生殖障碍无显著影响。PM2.5和NO2在女性和≥65岁患者中的相关性更强。在男性和<65岁的患者中，CO的相关性更强。PM2.5，NO2和CO是泌尿生殖系统发病的危险因素，应加强公共卫生干预措施，以保护弱势群体。
