METHODS: A literature search was performed from 1996 to 2023 to identify clinical studies on surgical treatment of OLTs. Screening was performed by 2 reviewers, who subsequently graded the quality using the methodological index for non-randomized studies (MINORS). The primary outcome was the frequency and qualitative assessment of reporting of size, morphology, and location.
RESULTS: Of 3,074 articles, 262 articles were included. This comprised a total of 11,785 patients. Size was reported in 248 (95%) of the articles and was described with a measure for surface area in 83%, however, in 56%, definition of measurement is unknown. Intraclass coefficient (ICC) value for the reliability of size measurement was 0.94 for computed tomography (CT) scan and 0.87 for MRI scan. Morphology was reported in 172 (66%) of the articles and using a classification system in 23% of the studies. Location was reported in 220 (84%) of the studies.
CONCLUSIONS: No consensus was found on the reporting of morphology, with non-validated classification systems and different terminologies used. For location, reporting in 9 zones is underreported. Size was well reported and measurements are more reliable for CT compared with MRI. As these prognostic factors guide clinical decision-making, we advocate the development of a standardized and validated OLT classification to reach uniform reporting in literature.
UNASSIGNED: Level III, systematic review.
方法:从1996年至2023年进行了文献检索,以确定有关OLT手术治疗的临床研究。筛选由2名评审员进行,随后使用非随机研究的方法学指数对质量进行分级(MINORS)。主要结果是报告规模的频率和定性评估,形态学,和位置。
结果:在3,074篇文章中,共包括262篇文章。这包括总共11,785名患者。尺寸在248(95%)的文章中报告,并描述了83%的表面积测量,然而,在56%中,测量的定义是未知的。大小测量可靠性的组内系数(ICC)值在计算机断层扫描(CT)扫描中为0.94,在MRI扫描中为0.87。在172(66%)的文章中报告了形态学,在23%的研究中使用了分类系统。在220(84%)的研究中报告了位置。
结论:在形态学报告方面未发现共识,使用未经验证的分类系统和不同的术语。对于位置,9个地区的报告被低估了。与MRI相比,CT的尺寸报告良好,测量结果更可靠。由于这些预后因素指导临床决策,我们主张开发标准化和经过验证的OLT分类,以达到文献中的统一报告。
■三级,系统回顾。