Abstract：
In recent years, several nasal cavity and sinus entities have been described with fusion genes. Salivary gland tumors with fusion genes will not be discussed in this article, but it should be kept in mind that accessory salivary glands are present in the nasal cavity and sinuses and can therefore lead to tumoral lesions. Entities with specific or more frequently described rearrangements in the nasal cavities and sinuses are DEK::AFF2 squamous cell carcinomas,;non-intestinal and non-salivary nasosinusal adenocarcinomas, some of which displaying ETV6 gene rearrangements; biphenotypic nasosinusal sarcomas, most of which displaying PAX3 gene rearrangements; and Ewing\'s adamantinoma-like sarcomas, which display the same rearrangements as conventional Ewing\'s sarcomas, mainly the EWSR1::FLI1 rearrangement. Each entity will be described morphologically, immunohistochemically, and prognostically.
摘要：
近年来,已经描述了几种具有融合基因的鼻腔和鼻窦实体。具有融合基因的唾液腺肿瘤将不在本文中讨论。但应该记住，副唾液腺存在于鼻腔和鼻窦中，因此可能导致肿瘤病变。在鼻腔和鼻窦中具有特定或更频繁描述的重排的实体是DEK::AFF2鳞状细胞癌，非肠和非唾液鼻窦腺癌，其中一些显示ETV6基因重排；双表型鼻嗜酸性肉瘤，其中大部分表现为PAX3基因重排；尤因的金刚烷瘤样肉瘤，显示与传统尤因肉瘤相同的重排，主要是EWSR1::FLI1重排。每个实体将在形态上进行描述，免疫组织化学，和预后。
