Abstract:
The ectopic liver lobe is a rare anomaly and is most frequently reported as a solitary mass. Herein, we report a case of multiple (two) ectopic liver lobes detected at an autopsy. A Japanese man in his 70s died of an infectious disease associated with acquired immunodeficiency syndrome (AIDS). Autopsy revealed the incidental finding of two 1-cm masses, located anterior to the inferior vena cava. Both masses were composed of liver tissue and had internal microscopic structures resembling the porta hepatis, consisting of an outflow bile duct and blood vessels. The outflow bile duct appeared to be continuous with the common bile duct, but the connection point of the outflow vessel was unclear. The liver tissue showed fibrous thickening of the central veins and portal venopathy, including fibrosis in the portal area as well as narrowing and loss of the portal veins. There was no evidence of congestion, fibrosis, biliary stasis, or neoplasm. The incidence of hepatocellular carcinoma is higher in the ectopic liver lobe than in the proper liver, presumably due to the abnormal circulation and bile excretion pathways. The patient also presented with portal venopathy; this suggests the presence of abnormal circulatory dynamics.
摘要:
异位肝叶是一种罕见的异常,最常报告为孤立性肿块。在这里,我们报告一例尸检时发现多(两)异位肝叶。一名70多岁的日本男子死于与获得性免疫缺陷综合症(AIDS)相关的传染病。尸检显示偶然发现了两个1厘米的肿块,位于下腔静脉前方。两个肿块均由肝组织组成,内部微观结构类似肝门,由流出胆管和血管组成。流出胆管似乎与胆总管相连,但是流出血管的连接点不清楚。肝组织表现为中央静脉纤维性增厚和门静脉病变,包括门静脉区域的纤维化以及门静脉的狭窄和丢失。没有拥堵的证据,纤维化,胆汁淤滞,或者肿瘤。异位肝叶肝细胞癌的发病率高于正常肝脏,可能是由于异常的循环和胆汁排泄途径。患者还出现门静脉病变;这表明存在异常的循环动力学。