PDF(Pubmed)
Abstract：
The report delineates the rare occurrence of uterine blastomycosis, an atypical systemic presentation of Blastomyces dermatitidis infection prevalent in North America. Focused on a 51-year-old immunocompetent female displaying abdominal pain and irregular vaginal bleeding, it underscores the intricate diagnostic hurdles posed by symptoms mirroring common gynecological conditions. Despite fewer than 10 recorded cases, the rarity of uterine involvement highlights the imperative for heightened clinical suspicion. The multifaceted diagnostic strategy integrates risk factors, travel history, imaging, and histopathological examinations. Emphasizing a multidisciplinary treatment helmed by gynecologists, pathologists, and infectious disease specialists, the utilization of antifungal agents, notably itraconazole, is pivotal. Addressing the scarcity of literature and the condition\'s clinical resemblance to prevalent ailments, further research becomes paramount in devising tailored diagnostic and treatment protocols for uterine blastomycosis. This study enriches the existing literature by providing critical insights into a scarcely documented condition, contributing novel perspectives essential for clinical understanding and management strategies.
摘要：
该报告描述了子宫胚真菌病的罕见发生，在北美流行的皮肤芽胞杆菌感染的非典型全身表现。专注于一名51岁的有免疫能力的女性，表现出腹痛和不规则的阴道出血，它强调了反映常见妇科疾病的症状所带来的复杂诊断障碍。尽管记录的病例不到10例，子宫受累的稀有性凸显了增加临床怀疑的必要性。多方面的诊断策略综合了风险因素,旅行史,成像,和组织病理学检查。强调由妇科医生主持的多学科治疗，病理学家,和传染病专家，抗真菌药物的利用，尤其是伊曲康唑，是关键的。解决文献的稀缺性和这种疾病与普遍疾病的临床相似性，进一步的研究对于设计定制的子宫胚菌病诊断和治疗方案至关重要。这项研究通过提供对几乎没有记载的疾病的批判性见解，丰富了现有的文献。贡献了对临床理解和管理策略至关重要的新观点。
