Mesh : Adult Infant, Newborn Humans Infant, Premature Infant, Low Birth Weight Anemia, Neonatal Erythrocytes Erythrocytes, Abnormal

来  源:   DOI:10.7754/Clin.Lab.2023.230428

Abstract:
BACKGROUND: Peripheral blood film morphology in neonates is significantly different from the adults as neonatal erythrocytes show a marked heterogeneity. Moreover, there seem to be a more significant numbers of irregular shaped red blood cells such as stomatocytes, keratocytes, schistocytes, and acantocytes in newborns, particularly in preterm infants. This review study focused on the red blood cell morphology in term and preterm neonates to detect clues to distinguish between the peripheral blood film of newborns under physiological and pathological conditions.
METHODS: The peripheral blood findings and blood cell counts in preterm and term neonates were studied and compared to each other using available scientific databases and indexing systems such as PubMed and Google Scholar.
RESULTS: This approach is a simple, cost-effective, quick, and informative method to distinguish between physiological and pathological conditions in neonates and detect hematological disorders.
CONCLUSIONS: Peripheral blood film plays a crucial role in diagnosing anemia and blood-related diseases, determining the type of anemia, and identifying specific morphological abnormalities of red cell membrane disorders.
摘要:
背景:新生儿外周血膜形态与成人有显著差异,因为新生儿红细胞表现出明显的异质性。此外,似乎有更多的不规则形状的红细胞,如气孔细胞,角膜细胞,分裂细胞,和新生儿的腺细胞,尤其是早产儿。这项综述研究着重于足月和早产新生儿的红细胞形态,以检测线索,以区分生理和病理条件下新生儿的外周血膜。
方法:使用现有的科学数据库和索引系统,如PubMed和GoogleScholar,对早产和足月新生儿的外周血和血细胞计数进行了研究和比较。
结果:这种方法很简单,成本效益高,快,和提供信息的方法来区分新生儿的生理和病理状况,并检测血液系统疾病。
结论:外周血膜在贫血和血液相关疾病的诊断中起着至关重要的作用。确定贫血的类型,并识别红细胞膜疾病的特定形态异常。
公众号