关键词: endocrinology and diabetes euglycemic diabetic ketoacidosis sodium-glucose cotransporter-2 (sglt-2) inhibitors stress-related cardiomyopathy type 1 and type 2 diabetes mellitus

来  源:   DOI:10.7759/cureus.52122   PDF(Pubmed)

Abstract:
Euglycemic diabetic ketoacidosis (EDKA) is an uncommon subtype of diabetic ketoacidosis (DKA) which presents with similar laboratory findings to classic DKA with the exception of blood glucose levels being under 250 mg/dl. EDKA has several etiologies including pregnancy, starvation and the use of sodium-glucose cotransporter-2 inhibitors (SGLT-2). SGLT-2 inhibitors such as empagliflozin and dapagliflozin are increasing in popularity due to their positive benefits for patients with diabetes mellitus and cardiac disease. EDKA is underdiagnosed as it presents with blood sugar levels lower than expected in classic DKA. This case report describes a well-controlled type 2 diabetic patient prescribed an SGLT-2 inhibitor who developed EDKA after undergoing coronary angiography for acute heart failure.
摘要:
正常血糖糖尿病酮症酸中毒(EDKA)是一种罕见的糖尿病酮症酸中毒(DKA)亚型,其实验室发现与经典DKA相似,但血糖水平低于250mg/dl。EDKA有几种病因,包括怀孕,饥饿和钠-葡萄糖协同转运蛋白-2抑制剂(SGLT-2)的使用。SGLT-2抑制剂如依帕格列净和达格列净由于它们对糖尿病和心脏病患者的积极益处而越来越受欢迎。EDKA被诊断不足,因为它的血糖水平低于经典DKA的预期。该病例报告描述了一名控制良好的2型糖尿病患者,该患者在接受冠状动脉造影治疗急性心力衰竭后使用SGLT-2抑制剂开发了EDKA。
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