PDF(Pubmed)
Abstract：
UNASSIGNED: Ultrasound elastography is a simple non-invasive method for measuring tissue elasticity in relation to tissue fibrosis. The aim of this study was to compare echogenicity, volume and shear wave velocities of undescended vs normally descended testes.
UNASSIGNED: Sixty-six boys with undescended testes were included in this study. The median age range was 35.5 (10-118) months old. The cases included in this prospective study consisted of 66 patients with non-operated undescended testes, with 51 of them being affected unilaterally and 15 affected bilaterally, as diagnosed by physical examination. The control group consisted of 31 healthy boys without any particular health problems. This prospective study was performed by gray-scale ultrasonography and shear wave elastography in boys with undescended testes and healthy testes. The testicular volumes were established by ultrasound measurement, the echogenicity and shear wave elastography values were measured in boys with unilateral and bilateral undescended testes, and the results were compared with healthy boys\' testes and their contralateral testes. The stiffness values were recorded for speed (m/s) and elasticity (kPa), and the stiffness values of undescended testes were compared with the healthy control group.
UNASSIGNED: Echogenicity values were lower in the bilateral undescended testes group than in the healthy group, and the healthy group\'s echogenicity was normal (p <0.001). The ROC curve was used to identify a cut-off shear wave elastography value for predicting decreased testicular echogenicity by using average shear wave elastography values. The area under the curve for the undescended testes was 0.78 (95% CI: 0.70-0.85, sensitivity 83.7%, specificity 68.7%, p <0.001), with an average shear wave elastography value of 2.32 (m/s) for above the cut-off point indicates. This was found to be significantly associated with reduced echogenicity on gray-scale ultrasonography, suggesting that it may be correlated with fibrosis developing in patients with undescended testes.
UNASSIGNED: The study provides interesting findings in that it proposes an alternative non-invasive method for the assessment of testicular tissue in undescended testes. We used shear wave elastography to compare the stiffness of normal testes in both heathy patients and in the contralateral healthy testes of boys with undescended testes, with the values obtained for the undescended testes reflecting the level of fibrosis of the parenchyma. Another outcome of this study was observed in patients with unilateral undescended testes, where the normally descended testes showed increased shear wave elastography values, which could be an early indication of parenchymal change.
UNASSIGNED: Sixty-six boys with undescended testes were included in this study. The median age range was 35.5 (10-118) months old. The cases included in this prospective study consisted of 66 patients with non-operated undescended testes, with 51 of them being affected unilaterally and 15 affected bilaterally, as diagnosed by physical examination. The control group consisted of 31 healthy boys without any particular health problems. This prospective study was performed by gray-scale ultrasonography and shear wave elastography in boys with undescended testes and healthy testes. The testicular volumes were established by ultrasound measurement, the echogenicity and shear wave elastography values were measured in boys with unilateral and bilateral undescended testes, and the results were compared with healthy boys\' testes and their contralateral testes. The stiffness values were recorded for speed (m/s) and elasticity (kPa), and the stiffness values of undescended testes were compared with the healthy control group.
UNASSIGNED: Echogenicity values were lower in the bilateral undescended testes group than in the healthy group, and the healthy group\'s echogenicity was normal (p <0.001). The ROC curve was used to identify a cut-off shear wave elastography value for predicting decreased testicular echogenicity by using average shear wave elastography values. The area under the curve for the undescended testes was 0.78 (95% CI: 0.70-0.85, sensitivity 83.7%, specificity 68.7%, p <0.001), with an average shear wave elastography value of 2.32 (m/s) for above the cut-off point indicates. This was found to be significantly associated with reduced echogenicity on gray-scale ultrasonography, suggesting that it may be correlated with fibrosis developing in patients with undescended testes.
UNASSIGNED: The study provides interesting findings in that it proposes an alternative non-invasive method for the assessment of testicular tissue in undescended testes. We used shear wave elastography to compare the stiffness of normal testes in both heathy patients and in the contralateral healthy testes of boys with undescended testes, with the values obtained for the undescended testes reflecting the level of fibrosis of the parenchyma. Another outcome of this study was observed in patients with unilateral undescended testes, where the normally descended testes showed increased shear wave elastography values, which could be an early indication of parenchymal change.
摘要：
■超声弹性成像是一种简单的非侵入性方法，用于测量与组织纤维化有关的组织弹性。这项研究的目的是比较回声，未下降睾丸与正常下降睾丸的体积和剪切波速度。
■本研究纳入了66名睾丸未降的男孩。中位年龄范围为35.5（10-118）个月。这项前瞻性研究中包括的病例包括66例非手术的未降睾丸患者，其中51人受到单方面影响，15人受到双边影响，通过体检诊断。对照组由31名健康男孩组成，没有任何特殊的健康问题。这项前瞻性研究是通过灰度超声和剪切波弹性成像对睾丸未降和睾丸健康的男孩进行的。通过超声测量确定睾丸体积，在单侧和双侧睾丸未降的男孩中测量回声和剪切波弹性成像值，并将结果与健康男孩的睾丸及其对侧睾丸进行比较。记录速度（m/s）和弹性（kPa）的刚度值，将未降睾丸的刚度值与健康对照组进行比较。
■双侧未降睾丸组比健康组低，健康组回声正常(p<0.001)。ROC曲线用于确定剪切波弹性成像的截止值，以通过使用平均剪切波弹性成像值预测睾丸回声性降低。未降睾丸的曲线下面积为0.78（95％CI：0.70-0.85，灵敏度83.7％，特异性68.7%，p<0.001)，截止点以上的平均剪切波弹性成像值为2.32(m/s)表示。发现这与灰度超声检查的回声减少显着相关，提示它可能与睾丸未降患者的纤维化发展有关。
■该研究提供了有趣的发现，因为它提出了一种替代的非侵入性方法来评估未降睾丸中的睾丸组织。我们使用剪切波弹性成像来比较健康患者和睾丸未降男孩对侧健康睾丸的正常睾丸的硬度，未降睾丸获得的值反映了实质的纤维化水平。这项研究的另一个结果是在单侧睾丸未降的患者中观察到的，正常下降的睾丸显示剪切波弹性成像值增加，这可能是实质改变的早期迹象。
■本研究纳入了66名睾丸未降的男孩。中位年龄范围为35.5（10-118）个月。这项前瞻性研究中包括的病例包括66例非手术的未降睾丸患者，其中51人受到单方面影响，15人受到双边影响，通过体检诊断。对照组由31名健康男孩组成，没有任何特殊的健康问题。这项前瞻性研究是通过灰度超声和剪切波弹性成像对睾丸未降和睾丸健康的男孩进行的。通过超声测量确定睾丸体积，在单侧和双侧睾丸未降的男孩中测量回声和剪切波弹性成像值，并将结果与健康男孩的睾丸及其对侧睾丸进行比较。记录速度（m/s）和弹性（kPa）的刚度值，将未降睾丸的刚度值与健康对照组进行比较。
■双侧未降睾丸组比健康组低，健康组回声正常(p<0.001)。ROC曲线用于确定剪切波弹性成像的截止值，以通过使用平均剪切波弹性成像值预测睾丸回声性降低。未降睾丸的曲线下面积为0.78（95％CI：0.70-0.85，灵敏度83.7％，特异性68.7%，p<0.001)，截止点以上的平均剪切波弹性成像值为2.32(m/s)表示。发现这与灰度超声检查的回声减少显着相关，提示它可能与睾丸未降患者的纤维化发展有关。
■该研究提供了有趣的发现，因为它提出了一种替代的非侵入性方法来评估未降睾丸中的睾丸组织。我们使用剪切波弹性成像来比较健康患者和睾丸未降男孩对侧健康睾丸的正常睾丸的硬度，未降睾丸获得的值反映了实质的纤维化水平。这项研究的另一个结果是在单侧睾丸未降的患者中观察到的，正常下降的睾丸显示剪切波弹性成像值增加，这可能是实质改变的早期迹象。
