PDF(Pubmed)
Abstract：
Although hematuria is not life-threatening, some could be the result of a more severe condition. Our objectives are to report on the prevalence and risk factors of asymptomatic microscopic hematuria (AMH) in the prospective epidemiological research studies of the Iranian adults (PERSIAN) Guilan cohort study (PGCS) population. This cross-sectional study was conducted from 2014 to 2017 and consisted of 10,520 individuals aged 35-70. Data collection was conducted using a questionnaire during a face-to-face interview. The urine analyses (UA) were done up to 2 h after sample collection. Based on a urine microscopy evaluation, AMH is defined as 3 or more red blood cells per high power field (HPF). Simple and multiple logistic regression analysis was conducted to explore factors associated with AMH. The prevalence of AMH in this study was 34.1% and was more prevalent in participants of older ages and female gender as well as those with low educational level, underweight-body mass index (BMI), high physical activity, smoking, alcohol consumption, and kidney stone disease. On the other hand, obesity, opium, and diabetes decreased the likelihood of AMH. The results of the present study shed light on the prevalence and risk factors of AMH and suggested that a significant portion of the study population is affected by AMH. Considering the lack of consensus on a definite clinical guideline for AMH in our country, the results of the present study could be used to design a unit algorithm for screening and therapy of AMH.
摘要：
虽然血尿并不危及生命,有些可能是病情更严重的结果。我们的目标是在伊朗成年人（PERSIAN）Guilan队列研究（PGCS）人群的前瞻性流行病学研究中报告无症状镜下血尿（AMH）的患病率和危险因素。这项横断面研究于2014年至2017年进行，由10,520名35-70岁的人组成。在面对面访谈期间使用问卷进行数据收集。在样品收集后2小时内进行尿液分析(UA)。根据尿液显微镜评估，AMH被定义为每个高功率场(HPF)3个或更多个红细胞。进行简单和多元logistic回归分析以探讨与AMH相关的因素。这项研究中AMH的患病率为34.1％，在年龄较大，女性以及受教育程度较低的参与者中更为普遍。体重过轻-体重指数(BMI),高体力活动，吸烟,酒精消费,和肾结石疾病。另一方面,肥胖，鸦片,糖尿病降低了AMH的可能性。本研究的结果揭示了AMH的患病率和危险因素，并表明研究人群中有很大一部分受到AMH的影响。考虑到我国对AMH的明确临床指南缺乏共识，本研究结果可用于设计AMH筛查和治疗的单元算法.
