Abstract：
OBJECTIVE: To evaluate the analgaesic efficacy of tenoxicam and dexketoprofen in patients admitted to the Emergency Medicine (EM) Clinic with severe acute pain due to primary dysmenorrhea (PD).
METHODS: Randomised-controlled trial. Place and Duration of the Study: Emergency Medicine Clinic, Health Sciences University, Adana City Training and Research Hospital, Adana, Turkiye, from January to December 2022.
METHODS: Patients presenting with PD, were divided into two groups of 60 each, administered 50 mg dexketoprofen and 20 mg tenoxicam intravenously. Visual analogue scale (VAS) scores were recorded at the 15th, 30th, 60th, and 120th minutes. VAS scores and ΔVAS scores were compared with the effectiveness of drugs, the need for rescue drugs and its side-effects.
RESULTS: Intravenous (IV) dexketoprofen was administered to 60 of the patients and IV tenoxicam was administered to another 60. At the time of admission, mean VAS scores of the patients were 8.8 ± 0.9 for the dexketoprofen group and 8.6 ± 0.8 for the tenoxicam group. The VAS scores of the dexketoprofen group were found to be statistically significantly lower after 30 minutes with lower need for rescue analgaesics. ΔVAS scores of the dexketoprofen group were statistically significantly higher from the 30th minute.
CONCLUSIONS: According to the VAS scoring, IV dexketoprofen was a more effective drug than IV tenoxicam in patients who were admitted to the EM clinic with severe pain due to PD.
BACKGROUND: Dexketoprofen, Primary dysmenorrhea, VAS score.
METHODS: Randomised-controlled trial. Place and Duration of the Study: Emergency Medicine Clinic, Health Sciences University, Adana City Training and Research Hospital, Adana, Turkiye, from January to December 2022.
METHODS: Patients presenting with PD, were divided into two groups of 60 each, administered 50 mg dexketoprofen and 20 mg tenoxicam intravenously. Visual analogue scale (VAS) scores were recorded at the 15th, 30th, 60th, and 120th minutes. VAS scores and ΔVAS scores were compared with the effectiveness of drugs, the need for rescue drugs and its side-effects.
RESULTS: Intravenous (IV) dexketoprofen was administered to 60 of the patients and IV tenoxicam was administered to another 60. At the time of admission, mean VAS scores of the patients were 8.8 ± 0.9 for the dexketoprofen group and 8.6 ± 0.8 for the tenoxicam group. The VAS scores of the dexketoprofen group were found to be statistically significantly lower after 30 minutes with lower need for rescue analgaesics. ΔVAS scores of the dexketoprofen group were statistically significantly higher from the 30th minute.
CONCLUSIONS: According to the VAS scoring, IV dexketoprofen was a more effective drug than IV tenoxicam in patients who were admitted to the EM clinic with severe pain due to PD.
BACKGROUND: Dexketoprofen, Primary dysmenorrhea, VAS score.
摘要：
目的：评价替诺昔康和右酮洛芬对急诊医学（EM）门诊因原发性痛经（PD）引起严重急性疼痛的患者的镇痛效果。
方法：随机对照试验。研究的地点和持续时间：急诊医学诊所，健康科学大学,阿达纳市培训和研究医院，阿达纳,Turkiye,2022年1月至12月。
方法：出现PD的患者，分为两组，每组60人，静脉注射50mg右酮洛芬和20mg替诺昔康。15日记录视觉模拟量表(VAS)评分,30日,60,第120分钟.VAS评分和ΔVAS评分与药物的有效性进行比较,对救援药物的需求及其副作用。
结果：对60名患者给予静脉（IV）右酮洛芬，对另外60名患者给予IV替诺昔康。在录取的时候,右酮洛芬组患者的平均VAS评分为8.8±0.9,替诺昔康组患者的平均VAS评分为8.6±0.8.发现右酮洛芬组的VAS评分在30分钟后具有统计学上的显着降低，对抢救镇痛药的需求较低。从第30分钟开始，右酮洛芬组的ΔVAS评分在统计学上明显更高。
结论：根据VAS评分，在因PD引起严重疼痛而入院的EM诊所的患者中，IV右酮洛芬是比IV替诺昔康更有效的药物。
背景：右酮洛芬，原发性痛经,VAS评分。
方法：随机对照试验。研究的地点和持续时间：急诊医学诊所，健康科学大学,阿达纳市培训和研究医院，阿达纳,Turkiye,2022年1月至12月。
方法：出现PD的患者，分为两组，每组60人，静脉注射50mg右酮洛芬和20mg替诺昔康。15日记录视觉模拟量表(VAS)评分,30日,60,第120分钟.VAS评分和ΔVAS评分与药物的有效性进行比较,对救援药物的需求及其副作用。
结果：对60名患者给予静脉（IV）右酮洛芬，对另外60名患者给予IV替诺昔康。在录取的时候,右酮洛芬组患者的平均VAS评分为8.8±0.9,替诺昔康组患者的平均VAS评分为8.6±0.8.发现右酮洛芬组的VAS评分在30分钟后具有统计学上的显着降低，对抢救镇痛药的需求较低。从第30分钟开始，右酮洛芬组的ΔVAS评分在统计学上明显更高。
结论：根据VAS评分，在因PD引起严重疼痛而入院的EM诊所的患者中，IV右酮洛芬是比IV替诺昔康更有效的药物。
背景：右酮洛芬，原发性痛经,VAS评分。
