HLA-C*05:292N, a novel HLA-C null allele identified by next-generation sequencing.

HLA - C * 05: 292N,通过下一代测序鉴定的新 HLA - C 无效等位基因。

• 影响指数: 8.762
• 发表时间: 2024 Feb
• 来源期刊: HLA
• DOI: 10.1111/tan.15380
• PMID: 38342776
• 文章类型: Journal Article
• 中科院分区: Q4
• 方向: 医学
• 作者列表: Schmitt J,Gothot A

关键词: HLA-C; next generation sequencing; null allele

Mesh: Humans; HLA-C Antigens / genetics; Alleles; Genes, MHC Class I; High-Throughput Nucleotide Sequencing

Abstract

HLA-C*05:292N differs from HLA-C*05:01:01:08 by a frameshift mutation, a deletion at gDNA position 758.

摘要

HLA-C*05:292N与HLA-C*05:01:01:08的差异在于移码突变，在gDNA位置758的缺失。