关键词: Chronic effect Damaged liver tissue Japanese quail Reproductive ability Tribufos

Mesh : Humans Animals Rats Coturnix Chickens Reproduction Gonads Quail Organothiophosphates

来  源:   DOI:10.1016/j.chemosphere.2024.141430

Abstract:
As a cotton defoliator, tribufos (S,S,S-tributyl phosphorotrithioate) is widespread in the environment. It can cause neurotoxicity in chickens, reproductive toxicity in rats, and can also cause headaches and nausea in humans. However, little is known about its impact on the reproduction of birds. Here, by analyzing the differences in reproductive indexs and histopathological characteristics, we investigated the chronic effects of 32 mg a.i./kg, 160 mg a.i./kg and 800 mg a.i./kg tribufos treatment on the reproductive ability of Japanese quail (Coturnix japonica). The results indicated that 32 mg a.i./kg and 160 mg a.i./kg tribufos treatment significantly reduced the food intake of quails, significantly increased the broken egg rate, and had adverse effects on gonads and liver tissue. The 160 mg a.i./kg tribufos treatment also significantly reduced the average egg production. Moreover, 800 mg a.i./kg treatment had significant negative effects on feed intake (FI), body weight (BW), eggshell thickness, egg production (EP), fertilization rate, hatchability and progeny 14-d survival rate, and it also significantly increased the broken egg rate. In addition, tribufos exposure caused lesions in quail gonads and liver tissue. Overall, our results revealed that tribufos had adverse effects on the reproductive ability of Japanese quail, especially at high concentrations.
摘要:
作为棉花脱叶器,既(S,S,三硫代磷酸S-三丁酯)在环境中广泛存在。它能对鸡造成神经毒性,大鼠生殖毒性,也会导致人类头痛和恶心。然而,人们对它对鸟类繁殖的影响知之甚少。这里,通过分析生殖指数和组织病理学特征的差异,我们调查了32mga.i./kg的慢性效应,160mga.i./kg和800mga.i./kg对日本鹌鹑(Coturnixjaponica)繁殖能力的影响。结果表明,32mga.i./kg和160mga.i./kg的丁香磷处理显著降低了鹌鹑的摄食量,显著提高了破蛋率,对性腺和肝组织有不良影响。160mga.i./kg的三磷处理也显著降低了平均产蛋量。此外,800mga.i./kg处理对采食量(FI)有显著的负面影响,体重(BW),蛋壳厚度,产蛋量(EP),受精率,孵化率和后代14天存活率,它也显著提高了破蛋率。此外,三叶草暴露导致鹌鹑性腺和肝组织病变。总的来说,我们的研究结果表明,秋千对日本鹌鹑的生殖能力有不利影响,特别是在高浓度。
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