Abstract：
BACKGROUND: Yoga is gradually being explored as a potential complementary intervention in addition to psychiatric drugs for schizophrenia. However, there are conflicts on the efficacy of yoga for schizophrenia. This meta-analysis was aimed to evaluate the association of yoga intervention with reductions on clinical symptoms and improvements in quality of life (QoL) as well as social functioning among schizophrenia.
METHODS: Systematic literature search was undertaken to identify all RCTs that compared yoga with active or passive controls for patients with schizophrenia from inception to July 2023. The outcomes were measurements of positive symptoms, negative symptoms, QoL and social functioning. Random-effects models were performed to calculate the effect sizes in the standardized mean differences reporting as Hedges\' s g statistic.
RESULTS: 19 studies enrolling 1274 participants with schizophrenia were included. Yoga had a medium effect on positive symptoms in the short term (Hedges\'s g = 0.31) and small effect in the long term (Hedges\'s g = 0.18). Medium significant effects were also found on negative symptoms in both the short term (Hedges\'s g = 0.44) and the long term (Hedges\'s g = 0.35). Yoga had a significant impact on improving both total QoL (Hedges\'s g = 0.34) and social functioning (Hedges\'s g = 0.45) with medium effect sizes.
CONCLUSIONS: Yoga was associated with significant reductions on negative and positive symptoms, and significant improvements in QoL as well as social functioning in patients with schizophrenia. Future research should explore the long-term efficacy of yoga for schizophrenia, encompassing more diverse populations.
METHODS: Systematic literature search was undertaken to identify all RCTs that compared yoga with active or passive controls for patients with schizophrenia from inception to July 2023. The outcomes were measurements of positive symptoms, negative symptoms, QoL and social functioning. Random-effects models were performed to calculate the effect sizes in the standardized mean differences reporting as Hedges\' s g statistic.
RESULTS: 19 studies enrolling 1274 participants with schizophrenia were included. Yoga had a medium effect on positive symptoms in the short term (Hedges\'s g = 0.31) and small effect in the long term (Hedges\'s g = 0.18). Medium significant effects were also found on negative symptoms in both the short term (Hedges\'s g = 0.44) and the long term (Hedges\'s g = 0.35). Yoga had a significant impact on improving both total QoL (Hedges\'s g = 0.34) and social functioning (Hedges\'s g = 0.45) with medium effect sizes.
CONCLUSIONS: Yoga was associated with significant reductions on negative and positive symptoms, and significant improvements in QoL as well as social functioning in patients with schizophrenia. Future research should explore the long-term efficacy of yoga for schizophrenia, encompassing more diverse populations.
摘要：
背景：除了治疗精神分裂症的精神药物外，瑜伽作为一种潜在的补充干预措施正在逐渐被探索。然而,瑜伽对精神分裂症的功效存在冲突。这项荟萃分析旨在评估瑜伽干预与精神分裂症患者临床症状减轻，生活质量（QoL）和社会功能改善的关系。
方法：进行了系统的文献检索，以确定从发病到2023年7月精神分裂症患者瑜伽与主动或被动对照的所有随机对照试验。结果是阳性症状的测量，阴性症状,QoL和社会功能。进行随机效应模型以计算作为Hedges的g统计量的标准化平均差异中的效应大小。
结果：纳入了纳入1274名精神分裂症患者的19项研究。瑜伽在短期内对阳性症状有中等影响（Hedges\sg=0.31），长期影响较小（Hedges\sg=0.18）。在短期（Hedges'sg=0.44）和长期（Hedges'sg=0.35）中也发现了对阴性症状的中等显着影响。瑜伽对改善中等效应大小的总QoL（Hedges\sg=0.34）和社会功能（Hedges\sg=0.45）都有重大影响。
结论：瑜伽与阴性和阳性症状的显著减少有关，精神分裂症患者的QoL和社会功能的显着改善。未来的研究应该探索瑜伽对精神分裂症的长期疗效，涵盖更多样化的人群。
方法：进行了系统的文献检索，以确定从发病到2023年7月精神分裂症患者瑜伽与主动或被动对照的所有随机对照试验。结果是阳性症状的测量，阴性症状,QoL和社会功能。进行随机效应模型以计算作为Hedges的g统计量的标准化平均差异中的效应大小。
结果：纳入了纳入1274名精神分裂症患者的19项研究。瑜伽在短期内对阳性症状有中等影响（Hedges\sg=0.31），长期影响较小（Hedges\sg=0.18）。在短期（Hedges'sg=0.44）和长期（Hedges'sg=0.35）中也发现了对阴性症状的中等显着影响。瑜伽对改善中等效应大小的总QoL（Hedges\sg=0.34）和社会功能（Hedges\sg=0.45）都有重大影响。
结论：瑜伽与阴性和阳性症状的显著减少有关，精神分裂症患者的QoL和社会功能的显着改善。未来的研究应该探索瑜伽对精神分裂症的长期疗效，涵盖更多样化的人群。
