Abstract：
The establishment of hematological reference intervals (RIs) is an important tool to assess the health status of animals and to evaluate the impact of diseases at individual and population levels. Nowadays, specific RIs of hematological parameters in newborn dromedary camel calves at birth and during the first week after birth, are lacking. Therefore, RIs for the hematological variables from a complete blood cell count were established in 47 healthy newborn dromedary calves (18 females and 29 males). Blood samples were collected within 2 h after birth (d0), at 24 h (d1), at 3 (d3) and 7 days (d7) after birth, and analyzed within 24 h. The RIs were described based on the 95% confidence interval, and possible differences among mean values due to age (sampling time) and sex were investigated. Statistical analysis showed that age affected all the hematological variables except MCV, MCH, and MCHC, indicating that the adaptational process to the extrauterine life continues for several days after birth; sex affected most of the hematological variables, with higher RBC and PLT count, HGB, PCV, neutrophil population and neutrophil:lymphocyte ratio at d7 in females compared to males. These findings suggest possible sex-based differences in the physiological maturation mechanisms and deserves further investigations. To the best of the authors\' knowledge, this is the first report of hematological RIs for newborn dromedary calves at birth up to 7 days of age; the RIs registered in the present study in newborns differ from those reported in adult dromedaries in literature, thus confirming the need for the adoption of separated reference ranges according to age also in the dromedary camel, as previously reported for other species.
摘要：
建立血液学参考间隔（RI）是评估动物健康状况和评估疾病在个体和群体水平上的影响的重要工具。如今,出生时和出生后第一周新生单峰骆驼小牛血液学参数的特异性RIs，缺乏。因此,在47只健康的新生单峰体小牛（18只雌性和29只雄性）中建立了来自全血细胞计数的血液学变量的RI。在出生后2小时内收集血样（d0），在24小时（d1），在出生后3（d3）和7天（d7），并在24小时内进行分析。RI基于95%置信区间进行描述，并调查了由于年龄（采样时间）和性别引起的平均值之间的可能差异。统计学分析显示年龄影响除MCV外的所有血液学变量,MCH,和MCHC,这表明对宫外生活的适应过程在出生后持续了几天；性别影响了大多数血液学变量，红细胞和血小板计数较高，HGB,PCV,中性粒细胞数量和中性粒细胞：d7时女性与男性的淋巴细胞比率。这些发现表明生理成熟机制可能存在性别差异，值得进一步研究。据作者所知，这是出生至7日龄的新生单峰体小牛的血液学RIs的第一份报告；本研究中登记的新生儿RIs与文献中报道的成人单峰体不同，从而证实了在单峰骆驼中也需要根据年龄采用分开的参考范围，正如以前报道的其他物种。
