关键词: breakthrough mucormycosis diagnosis management mucormycosis zygomycosis

来  源:   DOI:10.3390/diagnostics14030314   PDF(Pubmed)

Abstract:
Mucormycosis is an infrequent but fatal illness that mainly affects patients with uncontrolled diabetes mellitus, diabetic ketoacidosis, solid and hematologic neoplasms, organ transplantation, chronic steroid intake, prolonged neutropenia, iron overload states, neonatal prematurity, severe malnutrition, and HIV. Many cases were reported across the world recently following the COVID-19 pandemic. Recent research has led to a better understanding of the pathogenesis of the disease, and global guidelines are now available for managing this serious infection. Herein, we comprehensively review the etiological agents, pathogenesis, clinical presentations, diagnosis, and management of mucormycosis.
摘要:
毛霉菌病是一种罕见但致命的疾病,主要影响不受控制的糖尿病患者。糖尿病酮症酸中毒,实体和血液肿瘤,器官移植,长期服用类固醇,持续的中性粒细胞减少症,铁过载状态,新生儿早产,严重的营养不良,和艾滋病毒。在COVID-19大流行之后,最近世界各地报告了许多病例。最近的研究使人们对这种疾病的发病机理有了更好的了解,和全球指南现在可用来管理这种严重的感染。在这里,我们全面审查了病因,发病机制,临床表现,诊断,和毛霉菌病的管理。
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