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Abstract：
Background: Vertebral compression fractures (VCFs) are the most common fragility fractures associated with low-energy injury mechanisms in postmenopausal women with osteoporosis. No clear consensus is currently available on the optimal timing for surgical intervention in specific cases. Methods: This study examined the correlations between sagittal parameters, functional scores, and the appropriate timing for surgical intervention during the recovery stage in patients with osteoporosis with thoracolumbar (TL) vertebral body fractures. A total of 161 women aged ≥ 65 years with osteoporosis were included in the study. Spinal sagittal parameters from standing plain films and functional outcomes as the Oswestry disability index (ODI) and the visual analogue scale (VAS) were collected. Results: We found that TL junction Cobb angle was significantly correlated with ODI > 30 (p < 0.001) and VAS > 6 (p < 0.001) and the discriminative values for predicting ODI > 30 and VAS > 6 were a TL kyphotic angle of 14.5° and 13.5°, respectively. Among women aged ≥ 65 years with osteoporosis, the back pain and functional impairment observed within 6 months following a compression fracture are associated with a greater TL kyphosis angle. Conclusions: This suggests that a more proactive approach may be necessary when addressing the conditions of these patients.
摘要：
背景：椎体压缩性骨折（VCFs）是绝经后骨质疏松症妇女中最常见的与低能量损伤机制相关的脆性骨折。在特定情况下，目前尚无关于手术干预的最佳时机的明确共识。方法：本研究检查矢状参数之间的相关性，功能分数，以及骨质疏松伴胸腰椎（TL）椎体骨折患者恢复期手术干预的合适时机。共有161名年龄≥65岁的骨质疏松症女性被纳入研究。收集站立平片的脊柱矢状参数和功能结局，如Oswestry残疾指数（ODI）和视觉模拟量表（VAS）。结果：我们发现TL连接Cobb角与ODI>30（p<0.001）和VAS>6（p<0.001）显着相关，预测ODI>30和VAS>6的判别值是TL后倾角为14.5°和13.5°，分别。在年龄≥65岁的骨质疏松症女性中，压缩骨折后6个月内观察到的背痛和功能障碍与较大的TL后凸角度相关。结论：这表明，在解决这些患者的病情时，可能需要采取更积极的方法。
