Abstract：
The present case reports a bacteremia due to Lachnoanaerobaculum umeaense (a Gram-positive, filamentous, rod-shaped, anaerobic, spore-forming bacillus present in the human oral microbiota) in a patient treated for acute myeloid leukemia. After failed identification by MALDI-TOF, identification was done by sequencing of 16s rRNA. The patient was successfully treated with Amoxicillin-clavulanic acid and ciprofloxacin for seven days. Comparison of V1-V3 regions of the bacterial 16S rRNA gene gene with published sequences failed to classify the strain as pathogenic or non-pathogenic based on this phylogenetic classification alone. Although Lachnoanaerobaculum gingivalis are known to be associated with bacteremia in patients with acute myeloid leukemia, this clinical case of infection by L. umeaense argues for further studies that will lead to more efficient classification of the infection by these microorganisms.
摘要：
本病例报告了由于Lachnoanaeraculumumeaense引起的菌血症（革兰氏阳性，丝状的,杆状,厌氧,存在于人类口腔微生物群中的孢子形成杆菌）在接受急性髓细胞性白血病治疗的患者中。MALDI-TOF识别失败后,通过16srRNA测序进行鉴定。患者用阿莫西林-克拉维酸和环丙沙星成功治疗7天。细菌16SrRNA基因的V1-V3区域与已发表序列的比较未能仅基于这种系统发育分类将菌株分类为致病性或非致病性。尽管已知齿龈菌与急性髓系白血病患者的菌血症有关，这种由L.umeaense感染的临床病例认为，进一步的研究将导致更有效的分类由这些微生物感染。
