PDF(Pubmed)
Abstract：
UNASSIGNED: To determine the diagnostic and localization value of 18F-fluorodeoxyglucose-positron emission tomography (PET)/computed tomography (CT) in patients with focal cortical dysplasia (FCD) who underwent epilepsy surgery.
UNASSIGNED: One hundred and eight patients with pathologically proven FCD who underwent surgery for refractory epilepsy were retrospectively analyzed. All patients underwent magnetic resonance imaging (MRI), 18F-FDG-PET/CT, and video electroencephalography. An MRI diagnosis of FCD was defined as MRI+. A PET/CT diagnosis of FCD was defined as PET/CT+.
UNASSIGNED: MRI and PET/CT detected FCD in 20.37% and 93.52% of patients, respectively. The difference was significant. Twenty-one patients were MRI+/PET+, 80 were MRI-/PET+, six were MRI-/PET-, and one was MRI+/PET-. The MRI positivity rate was lowest in patients with FCD type IIIa (5.6%, P < 0.05). Prevalence of MRI-/PET+ was highest in patients with FCD type IIIa (88.89%, P < 0.05).
UNASSIGNED: PET/CT is superior to MRI in detecting FCD. FCD type IIIa was more likely than other types to show MRI-/PET+. This suggests that PET/CT has particular diagnostic value for FCD type IIIa patients with negative MRI findings.
UNASSIGNED: One hundred and eight patients with pathologically proven FCD who underwent surgery for refractory epilepsy were retrospectively analyzed. All patients underwent magnetic resonance imaging (MRI), 18F-FDG-PET/CT, and video electroencephalography. An MRI diagnosis of FCD was defined as MRI+. A PET/CT diagnosis of FCD was defined as PET/CT+.
UNASSIGNED: MRI and PET/CT detected FCD in 20.37% and 93.52% of patients, respectively. The difference was significant. Twenty-one patients were MRI+/PET+, 80 were MRI-/PET+, six were MRI-/PET-, and one was MRI+/PET-. The MRI positivity rate was lowest in patients with FCD type IIIa (5.6%, P < 0.05). Prevalence of MRI-/PET+ was highest in patients with FCD type IIIa (88.89%, P < 0.05).
UNASSIGNED: PET/CT is superior to MRI in detecting FCD. FCD type IIIa was more likely than other types to show MRI-/PET+. This suggests that PET/CT has particular diagnostic value for FCD type IIIa patients with negative MRI findings.
摘要：
■确定18F-氟脱氧葡萄糖-正电子发射断层扫描（PET）/计算机断层扫描（CT）在接受癫痫手术的局灶性皮质发育不良（FCD）患者中的诊断和定位价值。
■回顾性分析108例经病理证实的FCD患者因难治性癫痫而接受手术治疗。所有患者均行磁共振成像(MRI),18F-FDG-PET/CT,和视频脑电图。FCD的MRI诊断定义为MRI+。FCD的PET/CT诊断定义为PET/CT+。
■MRI和PET/CT在20.37％和93.52％的患者中检测到FCD，分别。差异是显著的。21例患者MRI+/PET+,80为MRI-/PET+，六个是MRI-/PET-，一个是MRI+/PET-。FCDIIIa型患者的MRI阳性率最低(5.6%,P<0.05)。IIIa型FCD患者的MRI-/PET+患病率最高(88.89%,P<0.05)。
■PET/CT在检测FCD方面优于MRI。IIIa型FCD比其他类型更有可能显示MRI-/PET+。这表明PET/CT对MRI阴性的FCDIIIa型患者具有特殊的诊断价值。
■回顾性分析108例经病理证实的FCD患者因难治性癫痫而接受手术治疗。所有患者均行磁共振成像(MRI),18F-FDG-PET/CT,和视频脑电图。FCD的MRI诊断定义为MRI+。FCD的PET/CT诊断定义为PET/CT+。
■MRI和PET/CT在20.37％和93.52％的患者中检测到FCD，分别。差异是显著的。21例患者MRI+/PET+,80为MRI-/PET+，六个是MRI-/PET-，一个是MRI+/PET-。FCDIIIa型患者的MRI阳性率最低(5.6%,P<0.05)。IIIa型FCD患者的MRI-/PET+患病率最高(88.89%,P<0.05)。
■PET/CT在检测FCD方面优于MRI。IIIa型FCD比其他类型更有可能显示MRI-/PET+。这表明PET/CT对MRI阴性的FCDIIIa型患者具有特殊的诊断价值。
