关键词: hepatic cirrhosis hypersplenism partial splenic artery embolization portal venous blood flow velocity portal venous thrombosis

来  源:   DOI:10.1097/MS9.0000000000001577   PDF(Pubmed)

Abstract:
UNASSIGNED: To investigate risk factors for portal venous thrombosis (PVT) after partial splenic artery embolization (PSE) in hepatic cirrhosis patients.
UNASSIGNED: The authors retrospectively analyzed 151 hepatic cirrhosis patients with hypersplenism who underwent partial splenic artery embolization between January 2020 and December 2021. The patients were divided into a PVT group and a non-PVT group according to whether they had PVT after PSE. Univariate analyses were performed to select risk factors for PVT after PSE, and multivariate analysis was used to analyze variates with a value of P less than 0.1 in univariate analysis.
UNASSIGNED: There were 151 patients enroled in the study, with 22 patients in the PVT group and 129 patients in the non-PVT group. There was no significant difference in terms of age, sex, smoking, hypertension, diabetes, Child-Pugh between two groups. White blood cell (WBC) and platelet counts after PSE were significantly higher than those before PSE in both the PVT group and non-PVT group. Univariate analysis showed that portal venous blood flow velocity, ligation of oesophageal varices and WBC after PSE were found to have a P value less than 0.1. Multivariate analysis showed that portal venous blood flow velocity was a factor associated with PVT after PSE.
UNASSIGNED: Portal venous blood flow velocity was a factor associated with PVT after PSE. Portal venous blood flow velocity should be considered before patients undergo PSE.
摘要:
探讨肝硬化患者部分脾动脉栓塞(PSE)后门静脉血栓形成(PVT)的危险因素。
作者回顾性分析了在2020年1月至2021年12月期间接受部分脾动脉栓塞治疗的151例肝硬化脾功能亢进患者。根据PSE后是否发生PVT,将患者分为PVT组和非PVT组。进行单因素分析以选择PSE后PVT的危险因素,多变量分析用于分析单变量分析中P值小于0.1的变量。
有151名患者参加了这项研究,PVT组22例,非PVT组129例。在年龄方面没有显著差异,性别,吸烟,高血压,糖尿病,Child-Pugh在两组之间。PVT组和非PVT组PSE后的白细胞(WBC)和血小板计数均明显高于PSE前。单因素分析显示门静脉血流速度,PSE后食管静脉曲张结扎和WBC的P值小于0.1。多因素分析显示,门静脉血流速度是PSE后PVT的相关因素。
门静脉血流速度是PSE后PVT的相关因素。在患者接受PSE之前,应考虑门静脉血流速度。
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