Abstract:
Target Of Rapamycin (TOR) represents a ubiquitous kinase complex that has emerged as a central regulator of cell growth and metabolism in nearly all eukaryotic organisms. TOR is an evolutionarily conserved protein kinase, functioning as a central signaling hub that integrates diverse internal and external cues to regulate a multitude of biological processes. These processes collectively exert significant influence on plant growth, development, nutrient assimilation, photosynthesis, fruit ripening, and interactions with microorganisms. Within the plant domain, the TOR complex comprises three integral components: TOR, RAPTOR, and LST8. This comprehensive review provides insights into various facets of the TOR protein, encompassing its origin, structure, function, and the regulatory and signaling pathways operative in photosynthetic organisms. Additionally, we explore future perspectives related to this pivotal protein kinase.
摘要:
雷帕霉素靶蛋白(TOR)代表一种普遍存在的激酶复合物,在几乎所有真核生物中都是细胞生长和代谢的主要调节因子。TOR是一种进化保守的蛋白激酶,作为一个中央信号枢纽,整合各种内部和外部线索来调节多种生物过程。这些过程共同对植物生长产生重大影响,发展,营养同化,光合作用,果实成熟,以及与微生物的相互作用。在植物领域,TOR综合体包括三个组成部分:TOR,RAPTOR,LST8这篇全面的综述提供了对TOR蛋白各个方面的见解,包括它的起源,结构,函数,以及在光合生物中起作用的调控和信号通路。此外,我们探讨了与这种关键蛋白激酶相关的未来观点。