Abstract：
Malignant melanoma, a rare skin cancer in children, primarily affects individuals over 10 years old. Giant congenital nevi, found in about 1% of newborns, increases the risk. However, the development of melanoma from a pre-existing giant congenital nevus diagnosed during the neonatal period is exceptionally rare. We present a case of congenital melanoma in a newborn, where nodules grew on an existing nevus on the baby\'s back. Literature on managing such cases was reviewed. This case highlights the importance of considering malignant transformation in congenital nevi and the challenges in their management. Due to limited reported cases over 80 years, conclusive findings on survival and treatment options are difficult to provide. Clinicians should report outcomes to develop a management algorithm for neonatal melanoma. Further studies are needed to enhance understanding of causes and treatment for patients with congenital giant hairy nevi and associated melanoma.
摘要：
恶性黑色素瘤,一种罕见的儿童皮肤癌，主要影响10岁以上的人。巨大的先天性痣，在大约1%的新生儿中发现，增加了风险。然而,在新生儿期诊断出的先前存在的巨大先天性痣引起的黑色素瘤非常罕见。我们介绍了一个新生儿先天性黑色素瘤的病例，结节生长在婴儿背上现有的痣上。审查了有关管理此类案件的文献。此案例强调了考虑先天性痣恶性转化的重要性及其管理中的挑战。由于报告的病例超过80年，很难提供关于生存和治疗选择的结论性发现.临床医生应报告结果，以开发新生儿黑色素瘤的管理算法。需要进一步的研究来加深对先天性巨大毛痣和相关黑色素瘤患者的病因和治疗的了解。
