PDF(Pubmed)
Abstract：
Leukocytoclastic vasculitis (LCV) is a small-vessel vasculitis characterized by inflammation and damage to the walls of small blood vessels. It typically presents with palpable purpura and can be associated with various systemic conditions. Although its etiology is diverse, LCV has been associated with systemic diseases, infections, medications, and autoimmune disorders. Here, we present a case of LCV in a patient with decompensated heart failure. A 58-year-old man presented with progressively deteriorating swelling in both his lower limbs and scrotum, a persistent dry cough associated with minor ulcerative lesions on his shins, and a patchy rash with pustules and flat reddish spots. He was hospitalized three days prior due to atrial fibrillation and rapid ventricular rate, for which he was commenced on amiodarone. This rash persisted for three days, yet he denied experiencing any discomfort or itchiness along with it. Based on his clinical picture, laboratory evaluations, and imaging findings, he was diagnosed with LCV induced by amiodarone.
摘要：
白细胞碎裂性血管炎（LCV）是一种小血管血管炎，其特征是炎症和对小血管壁的损害。它通常表现为可触及的紫癜，并可能与各种全身状况有关。虽然其病因多样,LCV与全身性疾病相关，感染,药物,和自身免疫性疾病。这里,我们介绍了1例失代偿性心力衰竭患者的LCV病例.一名58岁男子的下肢和阴囊肿胀逐渐恶化，持续的干咳与胫骨上的轻微溃疡性病变有关，和斑片状皮疹，有脓疱和扁平的红色斑点。他三天前因心房颤动和快速心室率住院，他开始服用胺碘酮。这种皮疹持续了三天，然而他否认有任何不适或瘙痒。根据他的临床表现,实验室评估,和影像学发现，他被诊断为胺碘酮诱导的LCV。
