PDF(Pubmed)
Abstract：
Human T Lymphotropic Virus type 1 (HTLV-1) is a neglected retrovirus associated with many clinical disorders, most notably Adult T-cell Leukemia/Lymphoma and HTLV-1-Associated Myelopathy (HAM). Found in endemic clusters across the world, high prevalence has been reported in minoritized groups who suffer from health inequities. This study investigates the association between HTLV-1 prevalence and the following socioeconomic determinants of health: education, income, and employment, which are markers of health inequity.
A systematic review was conducted by searching the following databases: Ovid/Medline, Embase, Global Health Database, Web of Science, LILACS and SciELO. Primary studies in English, Spanish and Portuguese mentioning HTLV-1 and one of education, income and/or employment were included. A random-effects meta-analysis was performed, and odds ratios (OR) were calculated to determine the association between these socioeconomic determinants of health and HTLV-1 prevalence.
42 studies were included. The likelihood of having HTLV-1 was higher in individuals with less than completed primary education compared to those who completed primary education (OR 1.86 [95% CI 1.34-2.57]; p < 0.01). This may be because individuals with low education have reduced access to and understanding of health information, thus increasing the prevalence of risk factors associated with HTLV-1 infection. No other determinants were found to be statistically significant.
Fewer years of schooling are associated with increased likelihood of contracting HTLV-1. Therefore, health promotion materials and public health policies regarding HTLV-1 must consider those with lower educational levels to effectively reduce disease transmission.
https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=335004, identifier (CRD42022335004).
A systematic review was conducted by searching the following databases: Ovid/Medline, Embase, Global Health Database, Web of Science, LILACS and SciELO. Primary studies in English, Spanish and Portuguese mentioning HTLV-1 and one of education, income and/or employment were included. A random-effects meta-analysis was performed, and odds ratios (OR) were calculated to determine the association between these socioeconomic determinants of health and HTLV-1 prevalence.
42 studies were included. The likelihood of having HTLV-1 was higher in individuals with less than completed primary education compared to those who completed primary education (OR 1.86 [95% CI 1.34-2.57]; p < 0.01). This may be because individuals with low education have reduced access to and understanding of health information, thus increasing the prevalence of risk factors associated with HTLV-1 infection. No other determinants were found to be statistically significant.
Fewer years of schooling are associated with increased likelihood of contracting HTLV-1. Therefore, health promotion materials and public health policies regarding HTLV-1 must consider those with lower educational levels to effectively reduce disease transmission.
https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=335004, identifier (CRD42022335004).
摘要：
■人类嗜T淋巴细胞病毒1型（HTLV-1）是与许多临床疾病相关的被忽视的逆转录病毒，最值得注意的是成人T细胞白血病/淋巴瘤和HTLV-1相关脊髓病（HAM）。在世界各地的地方性集群中发现，据报道，患有健康不平等的少数族裔群体的患病率很高。本研究调查了HTLV-1患病率与以下健康社会经济决定因素之间的关联：教育，收入,就业,这是健康不平等的标志。
■通过搜索以下数据库进行了系统评价：Ovid/Medline，Embase,全球卫生数据库,WebofScience,LILACS和SciELO.小学英语学习，西班牙语和葡萄牙语提到HTLV-1和教育之一，收入和/或就业包括在内。进行了随机效应荟萃分析，计算比值比(OR),以确定这些健康的社会经济决定因素与HTLV-1患病率之间的关联.
■包括42项研究。与完成初等教育的人相比，初等教育不足的人患HTLV-1的可能性更高（OR1.86[95％CI1.34-2.57]；p<0.01）。这可能是因为受教育程度低的个人对健康信息的获取和理解减少了，从而增加了与HTLV-1感染相关的危险因素的患病率。没有发现其他决定因素具有统计学意义。
■受教育年限减少与感染HTLV-1的可能性增加有关。因此,关于HTLV-1的健康宣传材料和公共卫生政策必须考虑那些受教育程度较低的人，以有效减少疾病传播。
■https://www.crd.约克。AC.uk/prospro/display_record.php?RecordID=335004,标识符(CRD42022335004)。
■通过搜索以下数据库进行了系统评价：Ovid/Medline，Embase,全球卫生数据库,WebofScience,LILACS和SciELO.小学英语学习，西班牙语和葡萄牙语提到HTLV-1和教育之一，收入和/或就业包括在内。进行了随机效应荟萃分析，计算比值比(OR),以确定这些健康的社会经济决定因素与HTLV-1患病率之间的关联.
■包括42项研究。与完成初等教育的人相比，初等教育不足的人患HTLV-1的可能性更高（OR1.86[95％CI1.34-2.57]；p<0.01）。这可能是因为受教育程度低的个人对健康信息的获取和理解减少了，从而增加了与HTLV-1感染相关的危险因素的患病率。没有发现其他决定因素具有统计学意义。
■受教育年限减少与感染HTLV-1的可能性增加有关。因此,关于HTLV-1的健康宣传材料和公共卫生政策必须考虑那些受教育程度较低的人，以有效减少疾病传播。
■https://www.crd.约克。AC.uk/prospro/display_record.php?RecordID=335004,标识符(CRD42022335004)。
