Abstract：
OBJECTIVE: Myopia is one of the most common forms of refractive error. Most myopia manifests itself as a relative growth of the eye axis, resulting in a state in which light is projected in front of the retina after being refracted by the refractive system of the eyeball. So far, the specific pathogenesis of myopia is still not well explained, through the results of animal experiments, researchers have proposed various possible scenarios, but all these are based on animal models, and there may still be a certain gap with the mechanism of true myopia in humans. The most readily available in clinical work is aqueous humor obtained during cataract surgery, for which we reviewed these studies of aqueous humor samples from myopic patients.
METHODS: A systematic literature search was done on PubMed using key words including \"myopia,\" \"aqueous humor,\" and \"protein.\"
RESULTS: The results of existing aqueous humor studies have shown that the difference in substances in the aqueous humor of myopia is related to the degradation of the scleral matrix, chronic inflammation of the eye, pro-fibrosis, blood vessel production, and inhibition. There may be more than one reason associated with myopia progression.
CONCLUSIONS: The specific mechanism of myopia has not been fully elucidated. Therefore, the means of preventing and treating myopia should focus on inhibiting the degradation of the scleral matrix, promoting the proliferation of scleral collagen fibers, and alleviating chronic inflammation of the eyes. Further research into myopic aqueous humor may provide us with new insights.
METHODS: A systematic literature search was done on PubMed using key words including \"myopia,\" \"aqueous humor,\" and \"protein.\"
RESULTS: The results of existing aqueous humor studies have shown that the difference in substances in the aqueous humor of myopia is related to the degradation of the scleral matrix, chronic inflammation of the eye, pro-fibrosis, blood vessel production, and inhibition. There may be more than one reason associated with myopia progression.
CONCLUSIONS: The specific mechanism of myopia has not been fully elucidated. Therefore, the means of preventing and treating myopia should focus on inhibiting the degradation of the scleral matrix, promoting the proliferation of scleral collagen fibers, and alleviating chronic inflammation of the eyes. Further research into myopic aqueous humor may provide us with new insights.
摘要：
目的：近视是屈光不正的最常见形式之一。大多数近视表现为眼轴的相对增长，导致光在被眼球的折射系统折射后投射到视网膜前方的状态。到目前为止,近视的具体发病机制还没有很好的解释，通过动物实验的结果，研究人员提出了各种可能的方案，但是所有这些都是基于动物模型，与人类真性近视的机制可能还有一定差距。临床工作中最容易获得的是白内障手术期间获得的房水，为此，我们回顾了这些来自近视患者的房水样本的研究。
方法：在PubMed上进行了系统的文献检索，使用关键词包括“近视，\“\”房水，“和”蛋白质。\"
结果：现有的房水研究结果表明，近视房水中物质的差异与巩膜基质的降解有关，眼睛的慢性炎症，促纤维化，血管生成，和抑制。与近视进展相关的原因可能不止一个。
结论：近视的具体机制尚未完全阐明。因此,预防和治疗近视的手段应侧重于抑制巩膜基质的降解，促进巩膜胶原纤维的增殖，减轻眼睛的慢性炎症。对近视房水的进一步研究可能为我们提供新的见解。
方法：在PubMed上进行了系统的文献检索，使用关键词包括“近视，\“\”房水，“和”蛋白质。\"
结果：现有的房水研究结果表明，近视房水中物质的差异与巩膜基质的降解有关，眼睛的慢性炎症，促纤维化，血管生成，和抑制。与近视进展相关的原因可能不止一个。
结论：近视的具体机制尚未完全阐明。因此,预防和治疗近视的手段应侧重于抑制巩膜基质的降解，促进巩膜胶原纤维的增殖，减轻眼睛的慢性炎症。对近视房水的进一步研究可能为我们提供新的见解。
