关键词: PND laryngopharyngeal reflux nasal endoscopy nasal mucosa postnasal drip rhinitis

来  源:   DOI:10.1055/s-0043-1767799   PDF(Pubmed)

Abstract:
Introduction  Patients with chronic rhinitis suffer from postnasal drip (PND) but this symptom is not well addressed. Nasal endoscopy may aid in identifying PND. Well described endoscopic features of PND are presence of secretions in the posterior nasal cavity, diffuse erythema, and hemorrhagic spots in the nasopharynx, but these have not been formally studied. Objectives  The present study aims to assess the association of nasal endoscopic features with PND among rhinitis patients. This will guide clinicians to interpret the nasal endoscopic findings appropriately. Methods  Adults (≥ 18 years old) with chronic rhinitis were consecutively recruited at an Otorhinolaryngology outpatient clinic in a tertiary referral center. The patients were grouped into either \"Rhinitis with PND\" or \"Rhinitis only.\" The endoscopic features of PND were scored as: Secretions in the posterior nasal cavity (yes/no), erythema in the nasopharynx (none, roof only, diffuse), hemorrhagic spots (yes/no), then were compared between groups. Results  There were 98 patients included (age 32.32 ± 11.33 years old, 61.2% female, 61.2% PND). Presence of secretions in the posterior nasal cavity was associated with PND (\"Rhinitis with PND\" versus \"Rhinitis only,\" 78.3 versus 55.3; p  = 0.02; Odds ratio: 2.81; 95% confidence interval [CI]: 1.08-7.32). Diffuse erythema of the nasopharynx was more frequent in \"rhinitis only\" compared with those with PND (76.3 versus 53.3%; p  = 0.02). Hemorrhagic spots were equally present in both groups (11.7 versus 18.4%; p  = 0.35). Conclusion  Presence of secretions in the posterior nasal cavity may indicate bothersome PND among patients with rhinitis. Diffuse erythema of the nasopharynx and hemorrhagic spots are a nonspecific sign of inflammation.
摘要:
简介慢性鼻炎患者患有鼻后滴漏(PND),但这种症状没有得到很好的解决。鼻内窥镜检查可能有助于识别PND。良好描述的PND的内窥镜特征是鼻腔后部存在分泌物,弥漫性红斑,和鼻咽部的出血点,但是这些还没有被正式研究。目的本研究旨在评估鼻炎患者的鼻内镜特征与PND的相关性。这将指导临床医生适当地解释鼻内窥镜检查结果。方法在三级转诊中心的耳鼻咽喉科门诊连续招募患有慢性鼻炎的成年人(≥18岁)。将患者分为“伴PND的鼻炎”或“仅鼻炎”。“PND的内窥镜特征评分为:鼻腔后部分泌物(是/否),鼻咽部红斑(无,只有屋顶,different),出血点(是/否),然后进行组间比较。结果共纳入患者98例(年龄32.32±11.33岁,61.2%女性,61.2%PND)。鼻腔后部分泌物的存在与PND有关(“鼻炎伴PND”与“仅鼻炎,“78.3对55.3;p=0.02;赔率比:2.81;95%置信区间[CI]:1.08-7.32)。与PND相比,“仅鼻炎”的鼻咽弥漫性红斑更常见(76.3对53.3%;p=0.02)。出血点在两组中同样存在(11.7对18.4%;p=0.35)。结论鼻腔后部分泌物的存在可能表明鼻炎患者中PND令人烦恼。鼻咽部弥漫性红斑和出血点是炎症的非特异性征象。
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