Mesh : Humans Alcoholism / diagnosis therapy Alcohol Drinking Substance Withdrawal Syndrome / diagnosis Ethanol Biomarkers Glycerophospholipids

来  源:   DOI:10.1111/ajad.13516   PDF(Pubmed)

Abstract:
The decision to initiate pharmacotherapy for alcohol withdrawal is typically based on examining self-reported use of alcohol and symptoms of withdrawal. Phosphatidylethanol (PEth) is a biomarker that could aim in clinical decision-making in withdrawal management.
This report describes three cases highlighting the potential clinical utility of PEth in caring for individuals at risk for alcohol withdrawal.
Two of the cases received phenobarbital when their PEth showed that the risk of withdrawal was low and one case where PEth could have shown this was needed. The results were only available in a delayed fashion, however, could have been useful in informing clinical care.
PEth can be a useful tool if available without delay. PEth can be used to quickly rule out alcohol withdrawal and avoid misdiagnoses and prolonged hospital stays.
This is a clinical case study available looking at PEth and withdrawal in hospitalized patients. It proposes that PEth can be used as a way to quickly rule out alcohol withdrawal to avoid misdiagnoses and the possibility of a prolonged hospital stay.
摘要:
目的:开始戒酒药物治疗的决定通常是基于检查自我报告的酒精使用情况和戒断症状。磷脂酰乙醇(PEth)是一种生物标志物,可用于戒断管理的临床决策。
方法:本报告描述了三个案例,强调了PEth在照顾有酒精戒断风险的个体方面的潜在临床效用。
结果:其中两例患者接受苯巴比妥时,他们的PEth显示戒断风险较低,而一例患者可能需要接受苯巴比妥。结果只能以延迟的方式获得,然而,可能有助于为临床护理提供信息。
结论:如果没有延迟,PEth可以是一个有用的工具。PEth可用于快速排除酒精戒断,避免误诊和延长住院时间。
结论:这是一个临床案例研究,研究住院患者的PETH和停药。它建议使用PEth作为一种快速排除酒精戒断的方法,以避免误诊和长时间住院的可能性。
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