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Abstract：
UNASSIGNED: To determine the prevalence of hepatitis B virus (HBV) infection, knowledge regarding HBV, vaccination status, and associated factors among household contacts of HBV index cases in Mwanza, Tanzania.
UNASSIGNED: Between July and August 2023, a cross-sectional study involving 97 index cases and 402 household contacts was conducted. Data were collected using pre-tested structured questionnaire and blood samples were collected from household contacts for HBV surface antigen (HBsAg) testing.
UNASSIGNED: The prevalence of HBV among household contacts was 5.4% (95% confidence interval, 2.9-9.0) with a significantly high proportion observed in > 45 years (16.6%) and in males (9.9%). A total of 40.0% of the household contacts had completed the full HBV vaccination series. On multivariate analysis, being male was significantly associated with HBsAg positivity (odds ratio: 7.16, 95% confidence interval: 1.81-28.2, P = 0.005).
UNASSIGNED: About one-tenth of adults\' male household contacts were HBsAg positive. In addition, the majority of household contacts had poor to fair knowledge regarding HBV infection with more than half being unvaccinated against HBV. There is a need to enhance awareness and education regarding HBV infection among household contacts in Tanzania and other low- and middle-income countries.
UNASSIGNED: Between July and August 2023, a cross-sectional study involving 97 index cases and 402 household contacts was conducted. Data were collected using pre-tested structured questionnaire and blood samples were collected from household contacts for HBV surface antigen (HBsAg) testing.
UNASSIGNED: The prevalence of HBV among household contacts was 5.4% (95% confidence interval, 2.9-9.0) with a significantly high proportion observed in > 45 years (16.6%) and in males (9.9%). A total of 40.0% of the household contacts had completed the full HBV vaccination series. On multivariate analysis, being male was significantly associated with HBsAg positivity (odds ratio: 7.16, 95% confidence interval: 1.81-28.2, P = 0.005).
UNASSIGNED: About one-tenth of adults\' male household contacts were HBsAg positive. In addition, the majority of household contacts had poor to fair knowledge regarding HBV infection with more than half being unvaccinated against HBV. There is a need to enhance awareness and education regarding HBV infection among household contacts in Tanzania and other low- and middle-income countries.
摘要：
■为了确定乙型肝炎病毒（HBV）感染的患病率，关于HBV的知识，疫苗接种状况,姆万扎HBV指数病例家庭接触者的相关因素，坦桑尼亚。
■在2023年7月至8月之间，进行了一项涉及97个索引病例和402个家庭接触者的横断面研究。使用预先测试的结构化问卷收集数据，并从家庭接触者收集血液样本进行HBV表面抗原（HBsAg）测试。
■家庭接触者中HBV的患病率为5.4％（95％置信区间，2.9-9.0），在>45岁（16.6％）和男性（9.9％）中观察到的比例很高。共有40.0％的家庭接触者完成了完整的HBV疫苗接种系列。在多变量分析中，男性与HBsAg阳性显着相关（比值比：7.16，95％置信区间：1.81-28.2，P=0.005）。
■约十分之一的成年人\'男性家庭接触者为HBsAg阳性。此外,大多数家庭接触者对HBV感染缺乏公平知识,超过一半未接种HBV疫苗.有必要在坦桑尼亚和其他低收入和中等收入国家的家庭接触者中加强对HBV感染的认识和教育。
■在2023年7月至8月之间，进行了一项涉及97个索引病例和402个家庭接触者的横断面研究。使用预先测试的结构化问卷收集数据，并从家庭接触者收集血液样本进行HBV表面抗原（HBsAg）测试。
■家庭接触者中HBV的患病率为5.4％（95％置信区间，2.9-9.0），在>45岁（16.6％）和男性（9.9％）中观察到的比例很高。共有40.0％的家庭接触者完成了完整的HBV疫苗接种系列。在多变量分析中，男性与HBsAg阳性显着相关（比值比：7.16，95％置信区间：1.81-28.2，P=0.005）。
■约十分之一的成年人\'男性家庭接触者为HBsAg阳性。此外,大多数家庭接触者对HBV感染缺乏公平知识,超过一半未接种HBV疫苗.有必要在坦桑尼亚和其他低收入和中等收入国家的家庭接触者中加强对HBV感染的认识和教育。
