PDF(Pubmed)
Abstract：
Neurological problems are more frequently linked to dengue, a mosquito-transmitted virus common in tropical areas. This review study thoroughly examines the effects of dengue on adult males\' neurological systems. Dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS) can develop in severe cases of dengue fever caused by the dengue virus (DENV). Unsettlingly, it is thought that a sizable portion of DENV infections impact the central nervous system (CNS), which calls into question the former theory that the DENV is not neurotropic. This review dissects the many neurological manifestations of dengue, spanning from encephalopathy, encephalitis, and other CNS implications to peripheral neuromuscular issues, through the systematic analysis of publications gathered from PubMed. The essay emphasizes the immunological reactions brought on by DENV infections and offers a deeper understanding of the pathophysiology. Given that they exhibit similar first symptoms, Zika and chikungunya are two more illnesses that must be distinguished from dengue. The mainstay of current diagnostic methods is serum and cerebrospinal fluid (CSF) tests, although supportive care is still used. This review highlights the importance of tracking neurological symptoms in dengue patients and encourages more studies in this area.
摘要：
神经系统问题更经常与登革热有关，热带地区常见的蚊子传播病毒。这项综述研究彻底检查了登革热对成年男性神经系统的影响。登革热出血热（DHF）或登革热休克综合征（DSS）可在由登革热病毒（DENV）引起的严重登革热病例中发展。令人不安的是，据认为，相当一部分的DENV感染影响中枢神经系统（CNS），这质疑了前一种理论，即DENV不是神经性的。这篇综述剖析了登革热的许多神经系统表现，从脑病开始，脑炎,和其他中枢神经系统对周围神经肌肉问题的影响，通过对PubMed收集的出版物的系统分析。本文强调了DENV感染引起的免疫反应，并对其病理生理学有了更深入的了解。鉴于他们表现出相似的最初症状，寨卡和基孔肯雅病是另外两种必须与登革热区分开来的疾病。目前的诊断方法主要是血清和脑脊液(CSF)测试,尽管仍然使用支持性护理。这篇综述强调了追踪登革热患者神经症状的重要性，并鼓励在这一领域进行更多的研究。
