PDF(Pubmed)
Abstract：
UNASSIGNED: Alzheimer\'s disease (AD) is a genetically intricate neurodegenerative disorder. Studies on \"Ferroptosis in AD\", \"Pyroptosis in AD\", and \"Necroptosis in AD\" are becoming more prevalent and there is increasing evidence that they are closely related to AD. However, there has not yet been a thorough bibliometrics-based investigation on this subject.
UNASSIGNED: This study uses a bibliometric approach to visualize and analyze the literature within the field of three distinct types of cell death in AD and explores the current research hotspots and prospective research directions.
UNASSIGNED: We collected relevant articles from the Web of Science and used CiteSpace, VOS viewer, and Pajek to perform a visual analysis.
UNASSIGNED: A total of 123, 95, and 84 articles were published in \"Ferroptosis in AD\", \"Pyroptosis in AD\", and \"Necroptosis in AD\", respectively. Based on keywords analysis, we can observe that \"oxidative stress\" and \"lipid peroxidation\", \"cell death\" and \"activation\", and \"Nlrp3 inflammasome\" and \"activation\" were the three most prominent words in the field of \"Ferroptosis in AD\", \"Pyroptosis in AD\", and \"Necroptosis in AD\", respectively. Focusing on the breakout words in the keyword analysis, we reviewed the mechanisms of ferroptosis, pyroptosis, and necroptosis in AD. By mapping the time zones of the keywords, we speculated on the evolutionary trends of ferroptosis, pyrotosis, and necroptosis in AD.
UNASSIGNED: Our findings can help researchers grasp the research status of three types of cell death in AD and determine new directions for future research as soon as possible.
UNASSIGNED: This study uses a bibliometric approach to visualize and analyze the literature within the field of three distinct types of cell death in AD and explores the current research hotspots and prospective research directions.
UNASSIGNED: We collected relevant articles from the Web of Science and used CiteSpace, VOS viewer, and Pajek to perform a visual analysis.
UNASSIGNED: A total of 123, 95, and 84 articles were published in \"Ferroptosis in AD\", \"Pyroptosis in AD\", and \"Necroptosis in AD\", respectively. Based on keywords analysis, we can observe that \"oxidative stress\" and \"lipid peroxidation\", \"cell death\" and \"activation\", and \"Nlrp3 inflammasome\" and \"activation\" were the three most prominent words in the field of \"Ferroptosis in AD\", \"Pyroptosis in AD\", and \"Necroptosis in AD\", respectively. Focusing on the breakout words in the keyword analysis, we reviewed the mechanisms of ferroptosis, pyroptosis, and necroptosis in AD. By mapping the time zones of the keywords, we speculated on the evolutionary trends of ferroptosis, pyrotosis, and necroptosis in AD.
UNASSIGNED: Our findings can help researchers grasp the research status of three types of cell death in AD and determine new directions for future research as soon as possible.
摘要：
■阿尔茨海默病（AD）是一种遗传复杂的神经退行性疾病。关于“AD中的铁凋亡”的研究“AD中的焦亡”，和“AD中的坏死性凋亡”越来越普遍，越来越多的证据表明它们与AD密切相关。然而,尚未对此主题进行基于文献计量学的彻底调查。
■本研究采用文献计量学方法对AD中三种不同类型的细胞死亡领域内的文献进行可视化和分析，并探讨当前的研究热点和前瞻性研究方向。
■我们从WebofScience收集相关文章，并使用CiteSpace，VOS查看器,和Pajek进行可视化分析。
■共有123、95和84篇文章发表在“AD中的铁中毒”中，“AD中的焦亡”，和“AD中的坏死”，分别。基于关键词分析,我们可以观察到“氧化应激”和“脂质过氧化”，“细胞死亡”和“激活”，“Nlrp3炎性体”和“激活”是“AD中的Ferroptosis”领域中最突出的三个词，“AD中的焦亡”，和“AD中的坏死”，分别。关注关键词分析中的突发性词,我们回顾了铁死亡的机制，焦亡,和在AD中的坏死。通过映射关键字的时区，我们推测了铁性死亡的进化趋势，热解，和在AD中的坏死。
■我们的发现可以帮助研究人员掌握AD中三种细胞死亡类型的研究现状，并尽快确定未来研究的新方向。
■本研究采用文献计量学方法对AD中三种不同类型的细胞死亡领域内的文献进行可视化和分析，并探讨当前的研究热点和前瞻性研究方向。
■我们从WebofScience收集相关文章，并使用CiteSpace，VOS查看器,和Pajek进行可视化分析。
■共有123、95和84篇文章发表在“AD中的铁中毒”中，“AD中的焦亡”，和“AD中的坏死”，分别。基于关键词分析,我们可以观察到“氧化应激”和“脂质过氧化”，“细胞死亡”和“激活”，“Nlrp3炎性体”和“激活”是“AD中的Ferroptosis”领域中最突出的三个词，“AD中的焦亡”，和“AD中的坏死”，分别。关注关键词分析中的突发性词,我们回顾了铁死亡的机制，焦亡,和在AD中的坏死。通过映射关键字的时区，我们推测了铁性死亡的进化趋势，热解，和在AD中的坏死。
■我们的发现可以帮助研究人员掌握AD中三种细胞死亡类型的研究现状，并尽快确定未来研究的新方向。
