Abstract：
\"Pigmentibacter ruber\" was first reported in 2021, a novel bacterium of the family Silvanigrellaceae, isolated from human blood of the patient with aspiration pneumonia after the drowning accident in Republic of China. However, until now, there is only one report describing \"P. ruber\" infection, and no case of isolation from natural environment has been reported so far. Thus, the infectivity and pathogenicity of \"Pigmentibacter\" spp. has not been clearly understood. In this report, we described the fatal case of \"Pigmentibacter\" bacteremia subsequently occurred after aspiration pneumonia probably due to accidental ingestion of irrigation water in the elderly patient. Despite administration of broad-spectrum antibiotic, the patient dramatically deteriorated and eventually deceased. Whole-genome sequencing showed the strain isolated from the patient was identified as \"Pigmentibacter\" sp. (designated as strain Takaoka) and antimicrobial sensitivity testing showed it displayed high minimum inhibitory concentrations against various antibiotics including β-lactam. Further studies are needed to clarify the clinical characteristics of \"Pigmentibacter\" and its relative\'s infections and their antimicrobial sensitivity; however, the present case supported the clinical characteristics of \"Pigmentibacter\" infection, which can lead to bacteremia following aspiration pneumonia caused by mis-swallowing contaminated water, and poor outcome potentially due to multidrug resistances.
摘要：
“Pigmentibacterruber”于2021年首次报道，这是Silvanigrellaceae家族的一种新型细菌，从中华民国溺水事故后吸入性肺炎患者的人体血液中分离。然而,直到现在,只有一份报告描述了\“P。鲁伯感染，到目前为止，还没有报告与自然环境隔离的情况。因此，“Pigmentibacter”spp的传染性和致病性。还没有被清楚地理解。在这份报告中,我们描述了在吸入性肺炎后发生的“Pigmentibactert”菌血症的致命病例，可能是由于老年患者意外摄入灌溉水所致。尽管使用了广谱抗生素，患者急剧恶化并最终死亡。全基因组测序显示，从患者中分离出的菌株被鉴定为“Pigmentibacter”sp。（称为Takaoka菌株）和抗微生物敏感性测试表明，它对包括β-内酰胺在内的各种抗生素显示出较高的最低抑制浓度。需要进一步的研究来阐明“Pigmentibacter”及其相关感染的临床特征及其抗菌敏感性；然而，本病例支持“色素杆菌”感染的临床特征，这可能导致吸入性肺炎后菌血症，和不良的结果可能是由于多药耐药。
