Abstract：
BACKGROUND: Osteochondral lesions of the talus are common in patients suffering even minor trauma; timely diagnosis and treatment can prevent the development of early osteoarthritis. The objectives of this systematic review and meta-analysis were to evaluate the effects of additional procedures on arthroscopic ankle microperforations for osteochondral lesions.
METHODS: A systematic literature search was conducted using PubMed-Medline, Cochrane Central, and Google Scholar to select clinical studies analyzing the efficacy of platelet-rich plasma (PRP), hyaluronic acid (HA), and bone marrow concentrate (BMC) procedures. Ten articles following PRISMA guidelines with a total of 464 patients were included in this review. Quality assessment using MINORS was performed, and all studies demonstrated high quality.
RESULTS: The results of the systematic review showed benefits in all patients undergoing infiltrative therapy with PRP, hyaluronic acid, and BMC. The best results in terms of AOFAS score and VAS scale were found in patients undergoing PRP injection. The meta-analysis showed improvements in pain relief and return to daily activities in patients undergoing arthroscopic microperforations and PRP, although not reporting statistically significant results (p = 0.42).
CONCLUSIONS: All treatment strategies reported better scores compared to the control groups. Among the various treatments analyzed, the addition of PRP appears to be the most valuable probably for the larger population receiving this treatment, showing excellent outcomes in pain reduction, clinical outcomes, and return to daily activities.
METHODS: II.
METHODS: A systematic literature search was conducted using PubMed-Medline, Cochrane Central, and Google Scholar to select clinical studies analyzing the efficacy of platelet-rich plasma (PRP), hyaluronic acid (HA), and bone marrow concentrate (BMC) procedures. Ten articles following PRISMA guidelines with a total of 464 patients were included in this review. Quality assessment using MINORS was performed, and all studies demonstrated high quality.
RESULTS: The results of the systematic review showed benefits in all patients undergoing infiltrative therapy with PRP, hyaluronic acid, and BMC. The best results in terms of AOFAS score and VAS scale were found in patients undergoing PRP injection. The meta-analysis showed improvements in pain relief and return to daily activities in patients undergoing arthroscopic microperforations and PRP, although not reporting statistically significant results (p = 0.42).
CONCLUSIONS: All treatment strategies reported better scores compared to the control groups. Among the various treatments analyzed, the addition of PRP appears to be the most valuable probably for the larger population receiving this treatment, showing excellent outcomes in pain reduction, clinical outcomes, and return to daily activities.
METHODS: II.
摘要：
背景：距骨软骨病在即使是轻微创伤的患者中也很常见；及时诊断和治疗可以防止早期骨关节炎的发展。本系统评价和荟萃分析的目的是评估其他手术对骨软骨损伤关节镜下踝关节微穿孔的影响。
方法：使用PubMed-Medline进行了系统的文献检索，CochraneCentral,和谷歌学者选择分析富血小板血浆(PRP)疗效的临床研究，透明质酸（HA），和骨髓浓缩物(BMC)程序。这篇综述包括了10篇遵循PRISMA指南的文章，共有464例患者。使用MINORS进行质量评估，所有研究都证明了高质量。
结果：系统评价结果显示，所有接受PRP浸润治疗的患者均能获益，透明质酸，BMC。在接受PRP注射的患者中，AOFAS评分和VAS量表的效果最好。荟萃分析显示，接受关节镜微穿孔和PRP的患者在疼痛缓解和恢复日常活动方面有所改善，尽管没有报告统计学意义的结果（p=0.42）。
结论：与对照组相比，所有治疗策略的评分均较好。在分析的各种治疗方法中，对于接受这种治疗的更大人群来说，添加PRP似乎是最有价值的，在减轻疼痛方面表现出优异的效果，临床结果，回到日常活动中。
方法：II.
方法：使用PubMed-Medline进行了系统的文献检索，CochraneCentral,和谷歌学者选择分析富血小板血浆(PRP)疗效的临床研究，透明质酸（HA），和骨髓浓缩物(BMC)程序。这篇综述包括了10篇遵循PRISMA指南的文章，共有464例患者。使用MINORS进行质量评估，所有研究都证明了高质量。
结果：系统评价结果显示，所有接受PRP浸润治疗的患者均能获益，透明质酸，BMC。在接受PRP注射的患者中，AOFAS评分和VAS量表的效果最好。荟萃分析显示，接受关节镜微穿孔和PRP的患者在疼痛缓解和恢复日常活动方面有所改善，尽管没有报告统计学意义的结果（p=0.42）。
结论：与对照组相比，所有治疗策略的评分均较好。在分析的各种治疗方法中，对于接受这种治疗的更大人群来说，添加PRP似乎是最有价值的，在减轻疼痛方面表现出优异的效果，临床结果，回到日常活动中。
方法：II.
