Abstract：
OBJECTIVE: Sedation is used in intensive care units (ICU) to improve comfort and tolerance during mechanical ventilation, invasive interventions, and nursing care. In recent years, the use of inhalation anaesthetics for this purpose has increased. Our objective was to obtain and summarise the best evidence on inhaled sedation in adult patients in the ICU, and use this to help physicians choose the most appropriate approach in terms of the impact of sedation on clinical outcomes and the risk-benefit of the chosen strategy.
METHODS: Given the overall lack of literature and scientific evidence on various aspects of inhaled sedation in the ICU, we decided to use a Delphi method to achieve consensus among a group of 17 expert panellists. The processes was conducted over a 12-month period between 2022 and 2023, and followed the recommendations of the CREDES guidelines.
RESULTS: The results of the Delphi survey form the basis of these 39 recommendations - 23 with a strong consensus and 15 with a weak consensus.
CONCLUSIONS: The use of inhaled sedation in the ICU is a reliable and appropriate option in a wide variety of clinical scenarios. However, there are numerous aspects of the technique that require further study.
METHODS: Given the overall lack of literature and scientific evidence on various aspects of inhaled sedation in the ICU, we decided to use a Delphi method to achieve consensus among a group of 17 expert panellists. The processes was conducted over a 12-month period between 2022 and 2023, and followed the recommendations of the CREDES guidelines.
RESULTS: The results of the Delphi survey form the basis of these 39 recommendations - 23 with a strong consensus and 15 with a weak consensus.
CONCLUSIONS: The use of inhaled sedation in the ICU is a reliable and appropriate option in a wide variety of clinical scenarios. However, there are numerous aspects of the technique that require further study.
摘要：
目的：镇静用于重症监护病房（ICU），以提高机械通气期间的舒适度和耐受性，侵入性干预措施，和护理。近年来,用于此目的的吸入麻醉剂的使用已经增加。我们的目的是获得并总结ICU中成年患者吸入镇静的最佳证据。根据镇静对临床结局的影响以及所选策略的风险-收益,帮助医师选择最合适的方法.
方法：鉴于ICU中吸入性镇静的各个方面总体缺乏文献和科学证据，我们决定使用Delphi方法在17名专家小组成员中达成共识。该过程在2022年至2023年的12个月内进行，并遵循CREDES指南的建议。
结果：Delphi调查的结果构成了这39项建议的基础-23项具有很强的共识，15项具有较弱的共识。
结论：在ICU中使用吸入镇静剂在各种临床情况下都是可靠且适当的选择。然而,该技术有许多方面需要进一步研究。
方法：鉴于ICU中吸入性镇静的各个方面总体缺乏文献和科学证据，我们决定使用Delphi方法在17名专家小组成员中达成共识。该过程在2022年至2023年的12个月内进行，并遵循CREDES指南的建议。
结果：Delphi调查的结果构成了这39项建议的基础-23项具有很强的共识，15项具有较弱的共识。
结论：在ICU中使用吸入镇静剂在各种临床情况下都是可靠且适当的选择。然而,该技术有许多方面需要进一步研究。
