Abstract：
OBJECTIVE: This study aimed to investigate the influence factors of financial toxicity experienced by colorectal cancer patients after surgery. The results will provide deep insights for developing effective intervention strategies to address this common issue of colorectal cancer care.
METHODS: In this cross-sectional study, we recruited 213 postoperative patients with colorectal cancer from February 2023 to July 2023 in two major public hospitals. Patients completed the General Information Questionnaire, Comprehensive Scores for Financial Toxicity (COST), Self-perceived Burden Scale (SPBS), Family Resilience Questionnaire (FaREQ), and Social Support Rating Scale (SSRS). A multiple linear regression model was used to investigate the influence factors of financial toxicity.
RESULTS: The mean score of financial toxicity was medium (18.91 ± 7.90) in this study. Financial toxicity score was negatively correlated with self-perceived burden (r = -0.333, P < 0.01) and positively associated with family resilience (r = 0.365, P < 0.01) and social support (r = 0.388, P < 0.01). Via multiple linear regression analysis, we identified seven significant factors associated with financial toxicity, including family income [(95 %CI: 1.075-3.123); P = 0.000], self-perceived burden [(95 %CI: 0.300∼-0.038); P = 0.012], stoma [(95 %CI: 5.309∼-1.682); P = 0.000], social support [(95 %CI:0.058-0.407); P = 0.009], cancer stage [(95 %CI: 2.178∼-0.170); P = 0.022], postoperative duration [(95 %CI: 1.900∼-0.332); P = 0.005], and family resilience [(95 %CI: 0.028-0.203); P = 0.010].
CONCLUSIONS: Financial toxicity was prevalent among postoperative colorectal cancer patients. Additional support and early interventions should be given to high-risk patients, including those with stomas, advanced disease stages, or experiencing longer postoperative duration. Apart from demographic factors, we identified that self-perceived burden, family resilience, and social support were also associated with financial toxicity, providing a new perspective for developing effective strategies against financial toxicity.
METHODS: In this cross-sectional study, we recruited 213 postoperative patients with colorectal cancer from February 2023 to July 2023 in two major public hospitals. Patients completed the General Information Questionnaire, Comprehensive Scores for Financial Toxicity (COST), Self-perceived Burden Scale (SPBS), Family Resilience Questionnaire (FaREQ), and Social Support Rating Scale (SSRS). A multiple linear regression model was used to investigate the influence factors of financial toxicity.
RESULTS: The mean score of financial toxicity was medium (18.91 ± 7.90) in this study. Financial toxicity score was negatively correlated with self-perceived burden (r = -0.333, P < 0.01) and positively associated with family resilience (r = 0.365, P < 0.01) and social support (r = 0.388, P < 0.01). Via multiple linear regression analysis, we identified seven significant factors associated with financial toxicity, including family income [(95 %CI: 1.075-3.123); P = 0.000], self-perceived burden [(95 %CI: 0.300∼-0.038); P = 0.012], stoma [(95 %CI: 5.309∼-1.682); P = 0.000], social support [(95 %CI:0.058-0.407); P = 0.009], cancer stage [(95 %CI: 2.178∼-0.170); P = 0.022], postoperative duration [(95 %CI: 1.900∼-0.332); P = 0.005], and family resilience [(95 %CI: 0.028-0.203); P = 0.010].
CONCLUSIONS: Financial toxicity was prevalent among postoperative colorectal cancer patients. Additional support and early interventions should be given to high-risk patients, including those with stomas, advanced disease stages, or experiencing longer postoperative duration. Apart from demographic factors, we identified that self-perceived burden, family resilience, and social support were also associated with financial toxicity, providing a new perspective for developing effective strategies against financial toxicity.
摘要：
目的：本研究旨在探讨结直肠癌患者术后财务毒性的影响因素。研究结果将为制定有效的干预策略以解决结直肠癌护理这一常见问题提供深刻的见解。
方法：在这项横断面研究中，我们从2023年2月至2023年7月在两家主要公立医院招募了213例结直肠癌术后患者.患者填写了一般信息问卷，金融毒性综合得分(COST)，自我感知负担量表(SPBS)，家庭弹性问卷(Fareq)和社会支持评定量表(SSRS)。采用多元线性回归模型考察金融毒性的影响因素。
结果：在这项研究中，金融毒性的平均得分为中等（18.91±7.90）。经济毒性评分与自我感受负担呈负相关(r=-0.333,P<0.01),与家庭弹性(r=0.365,P<0.01)、社会支持(r=0.388,P<0.01)呈正相关。通过多元线性回归分析，我们确定了与金融毒性相关的七个重要因素，包括家庭收入[(95CI：1.075-3.123)；P=0.000]，自我感知负担[(95CI：0.300~-0.038)；P=0.012]，气孔[(95CI：5.309~-1.682)；P=0.000]，社会支持[（95CI：0.058-0.407）；P=0.009]，癌症分期[(95CI：2.178~-0.170)；P=0.022]，术后持续时间[（95CI：1.900~-0.332）；P=0.005]，和家庭弹性[(95CI：0.028-0.203)；P=0.010]。
结论：金融毒性在结直肠癌术后患者中普遍存在。对高危患者应给予额外的支持和早期干预,包括那些有气孔的，晚期疾病阶段，或经历较长的术后持续时间。除了人口因素，我们发现了自我感知的负担，家庭韧性，社会支持也与金融毒性有关，为制定有效的金融毒性战略提供了新的视角。
方法：在这项横断面研究中，我们从2023年2月至2023年7月在两家主要公立医院招募了213例结直肠癌术后患者.患者填写了一般信息问卷，金融毒性综合得分(COST)，自我感知负担量表(SPBS)，家庭弹性问卷(Fareq)和社会支持评定量表(SSRS)。采用多元线性回归模型考察金融毒性的影响因素。
结果：在这项研究中，金融毒性的平均得分为中等（18.91±7.90）。经济毒性评分与自我感受负担呈负相关(r=-0.333,P<0.01),与家庭弹性(r=0.365,P<0.01)、社会支持(r=0.388,P<0.01)呈正相关。通过多元线性回归分析，我们确定了与金融毒性相关的七个重要因素，包括家庭收入[(95CI：1.075-3.123)；P=0.000]，自我感知负担[(95CI：0.300~-0.038)；P=0.012]，气孔[(95CI：5.309~-1.682)；P=0.000]，社会支持[（95CI：0.058-0.407）；P=0.009]，癌症分期[(95CI：2.178~-0.170)；P=0.022]，术后持续时间[（95CI：1.900~-0.332）；P=0.005]，和家庭弹性[(95CI：0.028-0.203)；P=0.010]。
结论：金融毒性在结直肠癌术后患者中普遍存在。对高危患者应给予额外的支持和早期干预,包括那些有气孔的，晚期疾病阶段，或经历较长的术后持续时间。除了人口因素，我们发现了自我感知的负担，家庭韧性，社会支持也与金融毒性有关，为制定有效的金融毒性战略提供了新的视角。
