PDF(Pubmed)
Abstract：
BACKGROUND: We present a case of an inflammatory myofibroblastic tumor cured with a short period of steroid administration, a treatment previously unreported for such cases.
METHODS: A 49-year-old man had a chief complaint of chest pain for more than 3 days. Computed tomography (CT) revealed a tumoral lesion suspected to have infiltrated into the right first rib and intercostal muscles, with changes in lung parenchymal density around the lesion. The maximal standardized uptake value on 18 F-fluorodeoxyglucose positron emission tomography/computed tomography was high (16.73), consistent with tumor presence. CT-guided biopsy revealed an inflammatory myofibroblastic tumor with no distant metastases. Surgery was indicated based on the disease course. However, he had received an oral steroid before the preoperative contrast-enhanced CT scan due to a history of bronchial asthma, and subsequent CT showed that the tumor shrank in size after administration; he has been recurrence-free for more than a year.
CONCLUSIONS: Surgery is still the first choice for inflammatory myofibroblastic tumors, as the disease can metastasize and relapse; however, this condition can also be cured with a short period of steroid therapy.
METHODS: A 49-year-old man had a chief complaint of chest pain for more than 3 days. Computed tomography (CT) revealed a tumoral lesion suspected to have infiltrated into the right first rib and intercostal muscles, with changes in lung parenchymal density around the lesion. The maximal standardized uptake value on 18 F-fluorodeoxyglucose positron emission tomography/computed tomography was high (16.73), consistent with tumor presence. CT-guided biopsy revealed an inflammatory myofibroblastic tumor with no distant metastases. Surgery was indicated based on the disease course. However, he had received an oral steroid before the preoperative contrast-enhanced CT scan due to a history of bronchial asthma, and subsequent CT showed that the tumor shrank in size after administration; he has been recurrence-free for more than a year.
CONCLUSIONS: Surgery is still the first choice for inflammatory myofibroblastic tumors, as the disease can metastasize and relapse; however, this condition can also be cured with a short period of steroid therapy.
摘要：
背景：我们介绍了一个通过短期类固醇给药治愈的炎症性肌纤维母细胞瘤的病例，以前未报告此类病例的治疗方法。
方法：一名49岁男性主诉胸痛超过3天。计算机断层扫描（CT）显示怀疑肿瘤病变浸润到右第一肋骨和肋间肌，伴随病灶周围肺实质密度的变化。18F-氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描的最大标准化摄取值很高（16.73），与肿瘤的存在一致。CT引导活检显示炎性肌纤维母细胞瘤，无远处转移。根据病程指示手术。然而,由于支气管哮喘病史，他在术前对比增强CT扫描前接受了口服类固醇治疗，随后的CT显示肿瘤在给药后缩小；他已经一年多没有复发。
结论：手术仍然是炎性肌纤维母细胞瘤的首选，因为这种疾病可以转移和复发；然而，这种情况也可以通过短期的类固醇治疗来治愈。
方法：一名49岁男性主诉胸痛超过3天。计算机断层扫描（CT）显示怀疑肿瘤病变浸润到右第一肋骨和肋间肌，伴随病灶周围肺实质密度的变化。18F-氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描的最大标准化摄取值很高（16.73），与肿瘤的存在一致。CT引导活检显示炎性肌纤维母细胞瘤，无远处转移。根据病程指示手术。然而,由于支气管哮喘病史，他在术前对比增强CT扫描前接受了口服类固醇治疗，随后的CT显示肿瘤在给药后缩小；他已经一年多没有复发。
结论：手术仍然是炎性肌纤维母细胞瘤的首选，因为这种疾病可以转移和复发；然而，这种情况也可以通过短期的类固醇治疗来治愈。
