PDF(Pubmed)
Abstract：
BACKGROUND: The low-level laser therapy (LLLT) and low-intensity pulsed ultrasound (LIPUS) have been recently applied to control pain during orthodontic treatment.
OBJECTIVE: To evaluate and compare the effectiveness of LLLT and LIPUS in reducing pain induced by orthodontic separation.
METHODS: A single-blinded randomized controlled trial.
METHODS: One hundred and fifty patients were randomly assigned into three groups; LLLT group, LIPUS group, and control group. After 5 min from the separators\' placement, the first dose of the laser or the ultrasound was applied, the second dose was applied after 24 h, and the third dose was applied after 48 h on both maxillary and mandibular first molars. The exposure of laser was for 20 s at each point (maxillary and mandibular first molars), with an 810-nm aluminum-gallium-arsenide (AlGaAs) diode laser on continuous mode. The output power set at 150 mW, the energy density of 4 J/cm2, and a laser spot diameter of 7 mm were applied. Whereas the frequency of ultrasonic toothbrush was 1.6 MHz; and average output intensity was 0.2 W/cm2. The application was for 20 min (5 min on each first molar). The control group received the separators without another intervention. A Visual Analog Scale (VAS 100 mm) was used to assess pain intensity at several time intervals during the first four days after the separators\' placement.
RESULTS: A total of 145 patients were assessed. There was a significant difference in pain perception among the three groups after 5 min (P = .002). The maximum pain level was reached after 24 h. However, the laser group and the ultrasound group showed a statistically significant decrease in pain scores compared to the control group at all the assessment time points (P < .001). Whereas there was no difference between the laser group and the ultrasound group in reducing the pain scores (P > .05).
CONCLUSIONS: The LLLT and the LIPUS effectively reduce the separation pain when applied in multiple doses without differences between them.
BACKGROUND: This trial was registered with the German Clinical Trials Register (DRKS). ( https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID= DRKS00029991). Date of registration: 26/08/2022.
OBJECTIVE: To evaluate and compare the effectiveness of LLLT and LIPUS in reducing pain induced by orthodontic separation.
METHODS: A single-blinded randomized controlled trial.
METHODS: One hundred and fifty patients were randomly assigned into three groups; LLLT group, LIPUS group, and control group. After 5 min from the separators\' placement, the first dose of the laser or the ultrasound was applied, the second dose was applied after 24 h, and the third dose was applied after 48 h on both maxillary and mandibular first molars. The exposure of laser was for 20 s at each point (maxillary and mandibular first molars), with an 810-nm aluminum-gallium-arsenide (AlGaAs) diode laser on continuous mode. The output power set at 150 mW, the energy density of 4 J/cm2, and a laser spot diameter of 7 mm were applied. Whereas the frequency of ultrasonic toothbrush was 1.6 MHz; and average output intensity was 0.2 W/cm2. The application was for 20 min (5 min on each first molar). The control group received the separators without another intervention. A Visual Analog Scale (VAS 100 mm) was used to assess pain intensity at several time intervals during the first four days after the separators\' placement.
RESULTS: A total of 145 patients were assessed. There was a significant difference in pain perception among the three groups after 5 min (P = .002). The maximum pain level was reached after 24 h. However, the laser group and the ultrasound group showed a statistically significant decrease in pain scores compared to the control group at all the assessment time points (P < .001). Whereas there was no difference between the laser group and the ultrasound group in reducing the pain scores (P > .05).
CONCLUSIONS: The LLLT and the LIPUS effectively reduce the separation pain when applied in multiple doses without differences between them.
BACKGROUND: This trial was registered with the German Clinical Trials Register (DRKS). ( https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID= DRKS00029991). Date of registration: 26/08/2022.
摘要：
背景：最近已应用低水平激光治疗（LLLT）和低强度脉冲超声（LIPUS）来控制正畸治疗期间的疼痛。
目的：评估和比较LLLT和LIPUS减轻正畸分离引起的疼痛的有效性。
方法：一项单盲随机对照试验。
方法：将150例患者随机分为三组；LLLT组，LIPUS集团,和对照组。放置分离器5分钟后，应用了第一剂量的激光或超声波，第二个剂量在24小时后应用，并在48小时后对上颌和下颌第一磨牙施加第三剂量。激光在每个点（上颌和下颌第一磨牙）照射20s，在连续模式下使用810nm铝-镓-砷化物（AlGaAs）二极管激光器。输出功率设置为150mW，施加4J/cm2的能量密度和7mm的激光光斑直径。超声波牙刷的频率为1.6MHz,平均输出强度为0.2W/cm2。施用20分钟(每个第一摩尔为5分钟)。对照组在没有其他干预的情况下接受了分离器。使用视觉模拟量表(VAS100mm)在放置分离器后的前四天期间以几个时间间隔评估疼痛强度。
结果：共评估了145例患者。5min后，三组的疼痛感知差异有统计学意义（P=0.002）。24小时后达到最大疼痛水平。在所有评估时间点，激光组和超声组的疼痛评分均明显低于对照组（P<.001）。而激光组与超声组在降低疼痛评分方面无差异(P>.05)。
结论：当多剂量应用时，LLLT和LIPUS有效地减轻了分离疼痛，它们之间没有差异。
背景：该试验已在德国临床试验注册中心（DRKS）注册。(https://www.drks.de/drks_web/navigate。做什么？navigationId=审判。HTML&TRIAL_ID=DRKS00029991)。注册日期：2022年8月26日。
目的：评估和比较LLLT和LIPUS减轻正畸分离引起的疼痛的有效性。
方法：一项单盲随机对照试验。
方法：将150例患者随机分为三组；LLLT组，LIPUS集团,和对照组。放置分离器5分钟后，应用了第一剂量的激光或超声波，第二个剂量在24小时后应用，并在48小时后对上颌和下颌第一磨牙施加第三剂量。激光在每个点（上颌和下颌第一磨牙）照射20s，在连续模式下使用810nm铝-镓-砷化物（AlGaAs）二极管激光器。输出功率设置为150mW，施加4J/cm2的能量密度和7mm的激光光斑直径。超声波牙刷的频率为1.6MHz,平均输出强度为0.2W/cm2。施用20分钟(每个第一摩尔为5分钟)。对照组在没有其他干预的情况下接受了分离器。使用视觉模拟量表(VAS100mm)在放置分离器后的前四天期间以几个时间间隔评估疼痛强度。
结果：共评估了145例患者。5min后，三组的疼痛感知差异有统计学意义（P=0.002）。24小时后达到最大疼痛水平。在所有评估时间点，激光组和超声组的疼痛评分均明显低于对照组（P<.001）。而激光组与超声组在降低疼痛评分方面无差异(P>.05)。
结论：当多剂量应用时，LLLT和LIPUS有效地减轻了分离疼痛，它们之间没有差异。
背景：该试验已在德国临床试验注册中心（DRKS）注册。(https://www.drks.de/drks_web/navigate。做什么？navigationId=审判。HTML&TRIAL_ID=DRKS00029991)。注册日期：2022年8月26日。
