Abstract:
The evolutionary history of cells has been marked by drastic increases in complexity. Some hypothesize that such cellular complexification requires a massive energy flux as the origin of new features is hypothetically more energetically costly than their evolutionary maintenance. However, it remains unclear how increases in cellular complexity demand more energy. I propose that the early evolution of new genes with weak functions imposes higher energetic costs by overexpression before their functions are evolutionarily refined. In the long term, the accumulation of new genes deviates resources away from growth and reproduction. Accrued cellular complexity further requires additional infrastructure for its maintenance. Altogether, this suggests that larger and more complex cells are defined by increased survival but lower reproductive capacity.
摘要:
细胞的进化史以复杂性急剧增加为标志。一些人假设这种细胞复合需要巨大的能量通量,因为新特征的起源比它们的进化维护在能量上更昂贵。然而,目前尚不清楚细胞复杂性的增加如何需要更多的能量。我认为,具有弱功能的新基因的早期进化会在其功能被进化完善之前通过过度表达而增加更高的能量成本。从长远来看,新基因的积累使资源偏离了生长和繁殖。应计的蜂窝复杂性进一步需要额外的基础设施来进行维护。总之,这表明,更大和更复杂的细胞被定义为增加的存活率,但较低的生殖能力。