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Abstract：
To explore the effect of hypoproteinemia on cardiac function and prognosis in elderly male patients with chronic heart failure. Among the patients with chronic heart failure hospitalized in the General Hospital of Southern Theater Command from December 2014 to December 2015, 100 elderly male patients with chronic heart failure were selected. The patients were divided into 2 groups based on their serum albumin (ALB) levels: 53 cases in the normal group (ALB ≥ 35 g/L) and 47 cases in the hypoproteinemia group (ALB < 35 g/L). Using the method of prospective study, under the condition of routine treatment of heart failure, follow-up observation for 5 years, we collected relevant data and analyzed the level of serum ALB, cardiac function and prognosis of patients in these 2 groups. The mortality of patients in the hyporoteinemia group were significantly higher than those in the normal group. Left ventricular end-diastolic dimension (LVDD) and brain natriuretic peptide (BNP) in the normal group after 5 years were markedly lower compared with that in the hypoproteinemia group. The mortality of patients with chronic heart failure with hypoproteinemia were higher, and the present study indicated that the ALB level may be associated with the mortality of patients with chronic heart failure.
摘要：
探讨低蛋白血症对老年男性慢性心力衰竭患者心功能及预后的影响。选取2014年12月至2015年12月在南部战区总医院住院的慢性心力衰竭患者中,老年男性慢性心力衰竭患者100例。根据患者血清白蛋白(ALB)水平分为2组:正常组53例(ALB≥35g/L),低蛋白血症组47例(ALB<35g/L)。采用前瞻性研究的方法,在常规治疗心力衰竭的情况下，随访观察5年,收集相关数据,分析血清ALB水平,两组患者心功能及预后情况。低氧素血症组患者的死亡率明显高于正常组。5年后正常组左心室舒张末期内径（LVDD）和脑钠肽（BNP）明显低于低蛋白血症组。慢性心力衰竭合并低蛋白血症患者死亡率较高,本研究提示ALB水平可能与慢性心力衰竭患者的死亡率相关。
