PDF(Pubmed)
Abstract：
UNASSIGNED: Head and neck photoimmunotherapy (HN-PIT) uses a combination of drugs and laser illumination to specifically destroy tumor cells. Lemierre\'s syndrome is an infectious disease with severe systemic symptoms caused by prior infection in the pharyngeal region, leading to thrombophlebitis. Here, we report a case of Lemierre\'s syndrome that developed after HN-PIT for recurrent nasopharyngeal carcinoma.
UNASSIGNED: A 68-year-old male with nasopharyngeal carcinoma (squamous cell carcinoma) underwent HN-PIT after local recurrence with chemoradiation therapy. Three months after HN-PIT, the patient developed fever and neck pain, which led to a diagnosis of Lemierre\'s syndrome. The patient was treated with antibiotics and anticoagulants for at least 1 month. The patient\'s general condition and inflammatory findings on blood sampling showed gradual improvement, and a follow-up cervicothoracic computed tomography imaging showed that the venous thrombus had been obscured and the patient was doing well.
UNASSIGNED: HN-PIT is a high-risk procedure for the development of Lemierre\'s syndrome due to irradiation-induced mucositis, and anticipating the development of Lemierre\'s syndrome during HN-PIT is important.
UNASSIGNED: A 68-year-old male with nasopharyngeal carcinoma (squamous cell carcinoma) underwent HN-PIT after local recurrence with chemoradiation therapy. Three months after HN-PIT, the patient developed fever and neck pain, which led to a diagnosis of Lemierre\'s syndrome. The patient was treated with antibiotics and anticoagulants for at least 1 month. The patient\'s general condition and inflammatory findings on blood sampling showed gradual improvement, and a follow-up cervicothoracic computed tomography imaging showed that the venous thrombus had been obscured and the patient was doing well.
UNASSIGNED: HN-PIT is a high-risk procedure for the development of Lemierre\'s syndrome due to irradiation-induced mucositis, and anticipating the development of Lemierre\'s syndrome during HN-PIT is important.
摘要：
■头颈部光免疫疗法（HN-PIT）使用药物和激光照明的组合来特异性地破坏肿瘤细胞。Lemierre综合征是一种由咽部区域的先前感染引起的具有严重全身症状的传染病，导致血栓性静脉炎.这里,我们报道一例复发鼻咽癌患者HN-PIT后出现的Lemierre综合征。
■一名68岁男性鼻咽癌（鳞状细胞癌）患者在局部复发并接受放化疗后接受HN-PIT治疗。HN-PIT后三个月,病人出现发热和颈部疼痛,这导致了Lemierre综合征的诊断。患者接受抗生素和抗凝剂治疗至少1个月。患者的一般情况和血液取样的炎症表现逐渐改善，随访的颈胸计算机断层扫描成像显示静脉血栓已被掩盖，患者病情良好。
■HN-PIT是由辐射引起的粘膜炎引起的Lemierre综合征发展的高风险程序，预测HN-PIT期间Lemierre综合征的发展很重要。
■一名68岁男性鼻咽癌（鳞状细胞癌）患者在局部复发并接受放化疗后接受HN-PIT治疗。HN-PIT后三个月,病人出现发热和颈部疼痛,这导致了Lemierre综合征的诊断。患者接受抗生素和抗凝剂治疗至少1个月。患者的一般情况和血液取样的炎症表现逐渐改善，随访的颈胸计算机断层扫描成像显示静脉血栓已被掩盖，患者病情良好。
■HN-PIT是由辐射引起的粘膜炎引起的Lemierre综合征发展的高风险程序，预测HN-PIT期间Lemierre综合征的发展很重要。
