Abstract:
A 66-year-old man with a history of frequent diarrhea was diagnosed with rectal cancer with obstruction and a pelvic abscess. Following a transverse colostomy, he was referred to our hospital. The initial diagnosis was rectal cancer(cT4a N1bM0, cStage Ⅲb)and a pelvic abscess due to tumor perforation. To address this condition, we performed neoadjuvant chemotherapy using a combination of 5-fluorouracil, Leucovorin, oxaliplatin, and irinotecan(FOLFOXIRI). Following 6 courses of FOLFOXIRI, the abscess disappeared and no signs of tumor progression and distant metastases were detected. Subsequently, we performed radical resection with D3LD2 lymph node dissection, leading to a pathological diagnosis of ypT3N1aM0, ypStage Ⅲb. The patient then underwent adjuvant chemotherapy with capecitabine and oxaliplatin(CAPOX). No recurrence was observed after 9 months of follow-up.
摘要:
一名有频繁腹泻病史的66岁男子被诊断为直肠癌伴梗阻和盆腔脓肿。横向结肠造口术后,他被转诊到我们医院。最初诊断为直肠癌(cT4aN1bM0,cⅢb期)和因肿瘤穿孔引起的盆腔脓肿。为了解决这个问题,我们使用5-氟尿嘧啶联合进行新辅助化疗,亚叶酸,奥沙利铂,和伊立替康(FOLFOXIRI)。在FOLFOXIRI的6个课程之后,脓肿消失,未发现肿瘤进展和远处转移的迹象.随后,我们进行了D3LD2淋巴结清扫根治术,导致ypT3N1aM0,ypStageⅢb的病理诊断。然后患者接受卡培他滨和奥沙利铂(CAPOX)辅助化疗。随访9个月后无复发。