Abstract：
Clinical and pathologic characteristics of the invasive ductal carcinoma (IDC) presenting as a thick-walled breast cyst are little known. Three female patients were included in this report. A palpable, nontender breast lump was found in all cases. While mammography showed a hyperdense mass, ultrasonography demonstrated a thick-walled cystic mass. Magnetic resonance imaging clearly showed the cystic breast lesions with ring-like or irregular rim enhancement. A grade III IDC was confirmed in all cases. All IDCs but one were estrogen receptor negative, progesterone receptor negative, and human epidermal growth factor receptor 2 negative, with merely weak progesterone receptor positivity (5%) in one case. All cases underwent surgical management first and postoperative chemotherapy. Breast malignancy presenting as a thick-walled cystic mass could be a highly aggressive IDC, even triple-negative breast cancer. It is imperative for breast cancer-related practitioners to identify the potentially malignant cystic lesions timely and adopt appropriate management.
摘要：
表现为厚壁乳腺囊肿的浸润性导管癌（IDC）的临床和病理特征鲜为人知。本报告包括三名女性患者。一个明显的，在所有病例中都发现了未触痛的乳房肿块。虽然乳房X光检查显示高密度肿块，超声检查显示厚壁囊性肿块。磁共振成像清楚显示乳腺囊性病变呈环状或不规则边缘增强。所有病例均确认为III级IDC。所有的疾病都是雌激素受体阴性的，孕激素受体阴性,和人表皮生长因子受体2阴性，在一例中只有弱孕激素受体阳性（5％）。所有病例均接受手术治疗和术后化疗。表现为厚壁囊性肿块的乳腺恶性肿瘤可能是高度侵袭性的IDC，甚至是三阴性乳腺癌.乳腺癌相关从业者必须及时识别潜在的恶性囊性病变并采取适当的管理。
