Abstract：
BACKGROUND: Currently, the status of serological screening for toxoplasmosis in pregnant women in Spain is unknown, and there is no official recommendation. The objective of this study is to show the current practice of gestational screening for toxoplasmosis in hospitals belonging to the Spanish Network for Research on Congenital Toxoplasmosis (REIV-TOXO).
METHODS: An electronic survey was sent between April 2021 and September 2021 to investigators from 118 hospitals of REIV-TOXO, representing all Spanish regions. Nine items related to gestational screening for toxoplasmosis were collected. This information was compared with cases of congenital toxoplasmosis (CT) identified in REIV-TOXO to determine if these were diagnosed in the presence of gestational screening.
RESULTS: During the study period, serological screening was performed in 53.3% (63/118) hospitals, with variations between regions and even among hospitals within the same region. Testing performed in each trimester was the most common practice (57.7%), followed by a single determination (24.4%). 89.4% of CT cases between January 2015 and September 2021 were diagnosed due to gestational screening.
CONCLUSIONS: The decision to perform gestational screening for toxoplasmosis in Spain is highly heterogeneous, with significant local and regional differences. Despite this, screening still allows the diagnosis of most CT cases. It is urgent to have current epidemiological data to inform decision-making in public health.
METHODS: An electronic survey was sent between April 2021 and September 2021 to investigators from 118 hospitals of REIV-TOXO, representing all Spanish regions. Nine items related to gestational screening for toxoplasmosis were collected. This information was compared with cases of congenital toxoplasmosis (CT) identified in REIV-TOXO to determine if these were diagnosed in the presence of gestational screening.
RESULTS: During the study period, serological screening was performed in 53.3% (63/118) hospitals, with variations between regions and even among hospitals within the same region. Testing performed in each trimester was the most common practice (57.7%), followed by a single determination (24.4%). 89.4% of CT cases between January 2015 and September 2021 were diagnosed due to gestational screening.
CONCLUSIONS: The decision to perform gestational screening for toxoplasmosis in Spain is highly heterogeneous, with significant local and regional differences. Despite this, screening still allows the diagnosis of most CT cases. It is urgent to have current epidemiological data to inform decision-making in public health.
摘要：
背景：目前，西班牙孕妇弓形虫病的血清学筛查状况未知，也没有官方建议。这项研究的目的是显示西班牙先天性弓形虫病研究网络（REIV-TOXO）所属医院中弓形虫病的妊娠筛查方法。
方法：在2021年4月至2021年9月之间，向REIV-TOXO的118家医院的调查人员发送了一项电子调查，代表所有西班牙地区。收集了与弓形虫病妊娠筛查相关的9个项目。将此信息与REIV-TOXO中鉴定的先天性弓形虫病（CT）病例进行比较，以确定是否在进行妊娠筛查的情况下被诊断出。
结果：在研究期间，53.3%(63/118)的医院进行了血清学筛查，地区之间甚至同一地区内医院之间的差异。在每三个月进行的测试是最常见的做法（57.7％），其次是一次测定（24.4%）。2015年1月至2021年9月，89.4%的CT病例被诊断为妊娠筛查。
结论：在西班牙进行弓形虫病妊娠筛查的决定是高度异质性的，具有显著的局部和区域差异。尽管如此,筛查仍然可以诊断大多数CT病例。迫切需要当前的流行病学数据来为公共卫生决策提供信息。
方法：在2021年4月至2021年9月之间，向REIV-TOXO的118家医院的调查人员发送了一项电子调查，代表所有西班牙地区。收集了与弓形虫病妊娠筛查相关的9个项目。将此信息与REIV-TOXO中鉴定的先天性弓形虫病（CT）病例进行比较，以确定是否在进行妊娠筛查的情况下被诊断出。
结果：在研究期间，53.3%(63/118)的医院进行了血清学筛查，地区之间甚至同一地区内医院之间的差异。在每三个月进行的测试是最常见的做法（57.7％），其次是一次测定（24.4%）。2015年1月至2021年9月，89.4%的CT病例被诊断为妊娠筛查。
结论：在西班牙进行弓形虫病妊娠筛查的决定是高度异质性的，具有显著的局部和区域差异。尽管如此,筛查仍然可以诊断大多数CT病例。迫切需要当前的流行病学数据来为公共卫生决策提供信息。
