Abstract：
BACKGROUND: Despite rapid technological progress, some arrhythmias are still resistant to standard unipolar ablation. These include arrhythmias arising from the base of the heart, cardiac crux, or epicardium. Bipolar radiofrequency ablation (B-RFA) may be useful in some cases, however, data on the efficacy of this approach in various arrhythmia localizations are scarce. The aim of this study was to assess the efficacy of B-RFA in patients with ventricular arrhythmias originating from various locations, occurring refractory to standard unipolar ablation approaches.
METHODS: An observational, single center study was conducted over a 30-month period. B-RFA were performed using dedicated radio frequency (RF) generator and electroanatomic mapping system.
RESULTS: Twenty-four procedures, in 23 patients with a median (range) of 1 (1-2) previously failed unipolar ablation procedures, were included in the final analysis. There were 12 ablations of ventricular arrhythmias originating from interventricular septum with an acute success rate of 75%, and 12 from left ventricular (LV) summit with an acute success rate of 58%. The midterm success rate (median interquartile range follow-up of 205 days [188-338]) was 66% and 50%, respectively.
CONCLUSIONS: B-RFA is a promising method of catheter ablation for refractory cardiac arrhythmias. A higher success rate was observed in ablation for difficult ventricular arrhythmias originating from interventricular septal region than LV summit.
METHODS: An observational, single center study was conducted over a 30-month period. B-RFA were performed using dedicated radio frequency (RF) generator and electroanatomic mapping system.
RESULTS: Twenty-four procedures, in 23 patients with a median (range) of 1 (1-2) previously failed unipolar ablation procedures, were included in the final analysis. There were 12 ablations of ventricular arrhythmias originating from interventricular septum with an acute success rate of 75%, and 12 from left ventricular (LV) summit with an acute success rate of 58%. The midterm success rate (median interquartile range follow-up of 205 days [188-338]) was 66% and 50%, respectively.
CONCLUSIONS: B-RFA is a promising method of catheter ablation for refractory cardiac arrhythmias. A higher success rate was observed in ablation for difficult ventricular arrhythmias originating from interventricular septal region than LV summit.
摘要：
背景：尽管技术进步很快，一些心律失常对标准单极消融仍有抵抗力.这些包括心脏底部引起的心律失常，心脏症结所在,或者心外膜.双极射频消融（B-RFA）在某些情况下可能是有用的，然而,关于这种方法在各种心律失常定位中的疗效的数据很少.这项研究的目的是评估B-RFA对来自不同位置的室性心律失常患者的疗效。出现标准单极消融方法的难治性。
方法：观察性，单中心研究进行了30个月.使用专用射频(RF)发生器和电解剖标测系统进行B-RFA。
结果：24个程序，在23位先前失败的单极消融手术的中位数（范围）为1（1-2）的患者中，包括在最终分析中。有12例起源于室间隔的室性心律失常消融，急性成功率为75％。和12从左心室（LV）的顶峰，急性成功率为58％。中期成功率（中位数四分位距随访205天[188-338]）为66％和50％，分别。
结论：B-RFA是一种有前途的导管消融治疗顽固性心律失常的方法。对于起源于室间隔区的难治性室性心律失常，消融的成功率高于LV峰顶。
方法：观察性，单中心研究进行了30个月.使用专用射频(RF)发生器和电解剖标测系统进行B-RFA。
结果：24个程序，在23位先前失败的单极消融手术的中位数（范围）为1（1-2）的患者中，包括在最终分析中。有12例起源于室间隔的室性心律失常消融，急性成功率为75％。和12从左心室（LV）的顶峰，急性成功率为58％。中期成功率（中位数四分位距随访205天[188-338]）为66％和50％，分别。
结论：B-RFA是一种有前途的导管消融治疗顽固性心律失常的方法。对于起源于室间隔区的难治性室性心律失常，消融的成功率高于LV峰顶。
