PDF(Pubmed)
Abstract：
UNASSIGNED: Psoriatic arthritis (PsA) is a heterogeneous, chronic inflammatory disease that negatively impacts patients\' quality of life. Patient-reported outcome measures (PROMs) are used to capture patient perspectives in disease assessment, and physicians use the Disease Activity Index for Psoriatic Arthritis (DAPSA) to evaluate disease activity in PsA. The study aimed to assess the relationship between PROMs and the DAPSA score in consecutive outpatients affected by PsA.
UNASSIGNED: A cross-sectional study was conducted from March 2018 to October 2020 at the PsA clinic of the ARNAS Civico in Palermo (Italy), enrolling outpatients with PsA. Patients were assessed for their disease activity according to the DAPSA score, and PROMs, such as PHQ-9, HAQ, FACIT-F, and PsAID, were evaluated. Linear regression analysis evaluated the relationship between the DAPSA Score and the included PROMs.
UNASSIGNED: 158 PsA consecutive peripheral subset psoriatic arthritis outpatients were recruited. The median years of illness was 10.6 (9.3-11.9), and the median DAPSA score was 19.02 (9-33.1). The regression analysis highlighted a strong relationship between the DAPSA score and the PsAID (adjR2 26%, p < 0.0001), the FACIT-F (adjR2 25.4%, p < 0.0001), the HAQ (adjR2 23.7%, p < 0.0001), and PHQ-9 (adjR2 15%, p < 0.0001).
UNASSIGNED: PROMs are strongly associated with the DAPSA score, but it allows in-depth evaluation of the impact of the disease on different domains of PsA patients\' life.
UNASSIGNED: A cross-sectional study was conducted from March 2018 to October 2020 at the PsA clinic of the ARNAS Civico in Palermo (Italy), enrolling outpatients with PsA. Patients were assessed for their disease activity according to the DAPSA score, and PROMs, such as PHQ-9, HAQ, FACIT-F, and PsAID, were evaluated. Linear regression analysis evaluated the relationship between the DAPSA Score and the included PROMs.
UNASSIGNED: 158 PsA consecutive peripheral subset psoriatic arthritis outpatients were recruited. The median years of illness was 10.6 (9.3-11.9), and the median DAPSA score was 19.02 (9-33.1). The regression analysis highlighted a strong relationship between the DAPSA score and the PsAID (adjR2 26%, p < 0.0001), the FACIT-F (adjR2 25.4%, p < 0.0001), the HAQ (adjR2 23.7%, p < 0.0001), and PHQ-9 (adjR2 15%, p < 0.0001).
UNASSIGNED: PROMs are strongly associated with the DAPSA score, but it allows in-depth evaluation of the impact of the disease on different domains of PsA patients\' life.
摘要：
■银屑病关节炎（PsA）是一种异质性，对患者生活质量产生负面影响的慢性炎症性疾病。患者报告的结果指标（PROM）用于在疾病评估中捕获患者观点，医生使用Psoriatic关节炎疾病活动指数（DAPSA）评估PsA的疾病活动。该研究旨在评估PsA影响的连续门诊患者的PROM与DAPSA评分之间的关系。
■一项横断面研究于2018年3月至2020年10月在意大利巴勒莫的ARNASCivico的PsA诊所进行，纳入门诊PsA患者。根据DAPSA评分评估患者的疾病活动性，和PROMs，如PHQ-9、HAQ、FACIT-F,和PsAID，进行了评估。线性回归分析评估了DAPSA评分与所包括的PROM之间的关系。
■158PsA连续的外周子集银屑病关节炎门诊患者。中位患病年限为10.6（9.3-11.9），中位DAPSA评分为19.02(9-33.1).回归分析强调了DAPSA评分和PsAID之间的强关系(adjR226%，p<0.0001),FACIT-F(adjR225.4%，p<0.0001),HAQ(adjR223.7%，p<0.0001),和PHQ-9(adjR215%，p<0.0001)。
■PROM与DAPSA评分密切相关，但它可以深入评估疾病对PsA患者不同生活领域的影响。
■一项横断面研究于2018年3月至2020年10月在意大利巴勒莫的ARNASCivico的PsA诊所进行，纳入门诊PsA患者。根据DAPSA评分评估患者的疾病活动性，和PROMs，如PHQ-9、HAQ、FACIT-F,和PsAID，进行了评估。线性回归分析评估了DAPSA评分与所包括的PROM之间的关系。
■158PsA连续的外周子集银屑病关节炎门诊患者。中位患病年限为10.6（9.3-11.9），中位DAPSA评分为19.02(9-33.1).回归分析强调了DAPSA评分和PsAID之间的强关系(adjR226%，p<0.0001),FACIT-F(adjR225.4%，p<0.0001),HAQ(adjR223.7%，p<0.0001),和PHQ-9(adjR215%，p<0.0001)。
■PROM与DAPSA评分密切相关，但它可以深入评估疾病对PsA患者不同生活领域的影响。
