关键词: Bile duct development Biliary atresia Classification Pathological features

Mesh : Humans Biliary Atresia / diagnosis surgery Bile Ducts, Extrahepatic Liver

来  源:   DOI:10.1007/s00383-023-05627-3

Abstract:
Biliary atresia is an occlusive biliary disease involving intrahepatic and extrahepatic bile ducts. Its etiology and pathogenesis are unclear. There are many manifestations of bile duct involvement in biliary atresia, but little is known about its occurrence and development. In addition, different classification methods have been proposed in different periods of biliary atresia, each with its advantages and disadvantages. The combined application of biliary atresia classification will help to improve the survival rate of patients with native liver. Therefore, this article reviews the development, pathological features, and classification of intrahepatic and extrahepatic bile ducts in biliary atresia, to provide a reference for the study of the pathogenesis and the choice of treatment methods.
摘要:
胆道闭锁是一种闭塞性胆道疾病,涉及肝内和肝外胆管。其病因及发病机制尚不清楚。胆道闭锁胆管受累有多种表现,但是对它的发生和发展知之甚少。此外,在胆道闭锁的不同时期提出了不同的分类方法,每个都有其优点和缺点。胆道闭锁分级的联合应用将有助于提高天然肝脏患者的生存率。因此,本文回顾了发展,病理特征,胆道闭锁的肝内和肝外胆管的分类,为其发病机制的研究和治疗方法的选择提供参考。
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