Abstract：
Calcium ions (Ca2+ ) are crucial intracellular second messengers in eukaryotic cells. Upon pathogen perception, plants generate a transient and rapid increase in cytoplasmic Ca2+ levels, which is subsequently decoded by Ca2+ sensors and effectors to activate downstream immune responses. The elevation of cytosolic Ca2+ is commonly attributed to Ca2+ influx mediated by plasma membrane-localized Ca2+ -permeable channels. However, the contribution of Ca2+ release triggered by intracellular Ca2+ -permeable channels in shaping Ca2+ signaling associated with plant immunity remains poorly understood. This review discusses recent advances in understanding the mechanism underlying the shaping of Ca2+ signatures upon the activation of immune receptors, with particular emphasis on the identification of intracellular immune receptors as non-canonical Ca2+ -permeable channels. We also discuss the involvement of Ca2+ release from the endoplasmic reticulum in generating Ca2+ signaling during plant immunity.
摘要：
钙离子（Ca2）是真核细胞中至关重要的细胞内第二信使。根据病原体的感知，植物产生细胞质Ca2+水平的瞬时和快速增加，其随后被Ca2+传感器和效应子解码以激活下游免疫应答。细胞溶质Ca2的升高通常归因于质膜定位的Ca2可渗透通道介导的Ca2流入。然而,细胞内Ca2+渗透通道触发的Ca2+释放在形成与植物免疫相关的Ca2+信号中的贡献仍然知之甚少。这篇综述讨论了在了解免疫受体激活时形成Ca2标记的机制方面的最新进展，特别着重于将细胞内免疫受体鉴定为非规范的Ca2可渗透通道。我们还讨论了植物免疫过程中内质网释放Ca2信号的参与。
