关键词: adjuvant chemotherapy non-small cell lung cancer stage IB treatment visceral pleural invasion

来  源:   DOI:10.3389/fonc.2023.1310471   PDF(Pubmed)

Abstract:
With the increasing implementation of early lung cancer screening and the increasing emphasis on physical examinations, the early-stage lung cancer detection rate continues to rise. Visceral pleural invasion (VPI), which denotes the tumor\'s breach of the elastic layer or reaching the surface of the visceral pleura, stands as a pivotal factor that impacts the prognosis of patients with non-small cell lung cancer (NSCLC) and directly influences the pathological staging of early-stage cases. According to the latest 9th edition of the TNM staging system for NSCLC, even when the tumor diameter is less than 3 cm, the final T stage remains T2a if VPI is present. There is considerable controversy within the guidelines regarding treatment options for stage IB NSCLC, especially among patients exhibiting VPI. Moreover, the precise determination of VPI is important in guiding treatment selection and prognostic evaluation in individuals with NSCLC. This article aims to provide a comprehensive review of the current status and advancements in studies pertaining to stage IB NSCLC accompanied by VPI.
摘要:
随着肺癌早期筛查的日益实施和体检的日益重视,早期肺癌检出率持续上升。内脏胸膜侵犯(VPI),表示肿瘤突破弹性层或到达内脏胸膜表面,作为影响非小细胞肺癌(NSCLC)患者预后的关键因素,并直接影响早期病例的病理分期。根据最新的NSCLCTNM分期系统的第9版,即使肿瘤直径小于3厘米,如果VPI存在,则最后的T级保持T2a。关于IB期非小细胞肺癌的治疗方案,指南中有相当大的争议。尤其是表现为VPI的患者。此外,VPI的精确测定对于指导NSCLC患者的治疗选择和预后评估具有重要意义.本文旨在对伴有VPI的IB期NSCLC的研究现状和进展进行全面综述。
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