关键词: botanical drugs direct-acting antiviral agents (DAAs) hepatitis C hepatitis C virus hepatoprotective and antiviral properties of medicinal plants

来  源:   DOI:10.3389/fphar.2023.1334160   PDF(Pubmed)

Abstract:
Hepatitis C virus (HCV) infection is a significant global health concern, prompting the need for effective treatment strategies. This in-depth review critically assesses the landscape of HCV treatment, drawing parallels between traditional interferon/ribavirin therapy historically pivotal in HCV management and herbal approaches rooted in traditional and complementary medicine. Advancements in therapeutic development and enhanced clinical outcomes axis on a comprehensive understanding of the diverse HCV genome, its natural variations, pathogenesis, and the impact of dietary, social, environmental, and economic factors. A thorough analysis was conducted through reputable sources such as Science Direct, PubMed, Scopus, Web of Science, books, and dissertations. This review primarily focuses on the intricate nature of HCV genomes and explores the potential of botanical drugs in both preventing and treating HCV infections.
摘要:
丙型肝炎病毒(HCV)感染是一个重要的全球健康问题,提示需要有效的治疗策略。这篇深入的综述严格评估了HCV治疗的前景,在传统的干扰素/利巴韦林治疗与根植于传统和补充医学的草药方法之间具有相似之处。基于对多样化HCV基因组的全面理解,治疗发展的进步和临床结果的增强轴,它的自然变化,发病机制,以及饮食的影响,社会,环境,和经济因素。通过ScienceDirect等知名来源进行了彻底的分析,PubMed,Scopus,WebofScience,书籍,和论文。这篇综述主要关注HCV基因组的复杂性,并探讨植物药物在预防和治疗HCV感染方面的潜力。
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