关键词: hypertrophic osteoarthropathy lung adenocarcinoma paraneoplastic rheumatic disease periostitis polyarthritis

来  源:   DOI:10.7759/cureus.51145   PDF(Pubmed)

Abstract:
Hypertrophic osteoarthropathy is a paraneoplastic syndrome and is considered an important secondary cause of rheumatic disease. It typically manifests as tibial and femoral bone pain, with arthralgia or synovitis of adjacent joints also being common findings. Usually, musculoskeletal symptoms accompany the course of the disease, disappearing with treatment of the neoplasm and recurring coincidentally with the tumor relapse. The authors report a case of a patient with hypertrophic osteoarthropathy, whose etiological study allowed the diagnosis of a lung adenocarcinoma, particularly challenging due to the patient\'s young age and the absence of associated symptoms.
摘要:
肥大性骨关节病是一种副肿瘤综合征,被认为是风湿性疾病的重要次要原因。通常表现为胫骨和股骨疼痛,关节痛或相邻关节滑膜炎也是常见的发现。通常,肌肉骨骼症状伴随着疾病的进程,随着肿瘤的治疗而消失,并与肿瘤复发同时复发。作者报告一例肥厚性骨关节病,其病因研究允许诊断为肺腺癌,特别具有挑战性,由于患者的年龄小,没有相关的症状。
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