PDF(Pubmed)
Abstract：
Malignant melanoma is an aggressive neoplasm primarily involving the skin. They may arise de novo or from a premalignant melanocytic lesion. Melanomas are primarily known to occur in adults. Pediatric melanomas (PM) are rare and predominantly occur de novo following ultraviolet deoxyribonucleic acid (DNA) damage. They may also be associated with the presence of congenital melanocytic nevi. We report a rare case of a 6-year-old child with multiple melanocytic nevi subsequently diagnosed with melanoma of the back and metastatic disease.
摘要：
恶性黑色素瘤是主要累及皮肤的侵袭性肿瘤。它们可能从头或由恶性黑素细胞病变引起。已知黑色素瘤主要发生在成人中。小儿黑色素瘤（PM）很少见，主要是在紫外线脱氧核糖核酸（DNA）损伤后从头发生。它们也可能与先天性黑素细胞痣的存在有关。我们报告了一例罕见的6岁儿童，患有多发性黑素细胞痣，随后被诊断为背部黑色素瘤和转移性疾病。
