关键词: Hypertension Tanzania antihypertensive medications blood pressure hemodialysis

Mesh : Humans Male Female Middle Aged Antihypertensive Agents / therapeutic use Cross-Sectional Studies Tanzania / epidemiology Hypertension / drug therapy epidemiology Renal Dialysis Blood Pressure Hospitals Surveys and Questionnaires

来  源:   DOI:10.11604/pamj.2023.46.67.39778   PDF(Pubmed)

Abstract:
UNASSIGNED: hypertension is prevalent among patients attending hemodialysis. However, published information on hypertension management among patients on hemodialysis in African countries is scarce. This study assessed antihypertensive medication prescribing patterns and blood pressure control among patients with hypertension on hemodialysis in Tanzania.
UNASSIGNED: an analytical cross-sectional study was conducted at Muhimbili National Hospital in Dar es Salaam from April to June 2022. The study population consisted of patients with hypertension undergoing hemodialysis. Data on demographic, clinical characteristics and the antihypertensive medications used by the patients was collected using a structured questionnaire. Analysis was performed using Statistical Package for the Social Sciences software version 26. Uncontrolled pre-dialysis blood pressure determinants were assessed using a modified Poisson regression model. A p-value < 0.05 was considered statistically significant.
UNASSIGNED: out of 314 participants, the majority (68.2%, n= 214) were male, and the median age was 52 (interquartile range: 42, 60) years. Only 16.9% (n= 53) of patients had their pre-dialysis blood pressure controlled. The most frequent antihypertensive medications prescribed were calcium channel blockers (73.2%, n= 230). Patients with less than three dialysis sessions were 20% more likely to have uncontrolled blood pressure than those with three sessions in a week (adjusted prevalence ratio = 1.2).
UNASSIGNED: most patients on hemodialysis with hypertension had poor blood pressure control, according to the study. Patients with hypertension should be strongly encouraged to adhere to at least three hemodialysis treatments to achieve optimal blood pressure control.
摘要:
高血压在参加血液透析的患者中很普遍。然而,关于非洲国家血液透析患者高血压管理的公开信息很少.这项研究评估了坦桑尼亚血液透析高血压患者的抗高血压药物处方模式和血压控制。
于2022年4月至6月在达累斯萨拉姆的Muhimbili国家医院进行了一项分析性横断面研究。研究人群包括接受血液透析的高血压患者。人口统计数据,使用结构化问卷收集患者的临床特征和使用的抗高血压药物.使用社会科学软件版本26的统计软件包进行分析。使用改进的Poisson回归模型评估不受控制的透析前血压决定因素。P值<0.05被认为是统计学上显著的。
在314名参与者中,大多数(68.2%,n=214)是男性,中位年龄为52岁(四分位距:42,60)。只有16.9%(n=53)的患者透析前血压得到控制。最常见的抗高血压药物是钙通道阻滞剂(73.2%,n=230)。少于三次透析的患者比一周三次透析的患者血压失控的可能性高20%(调整后的患病率=1.2)。
大多数血液透析合并高血压的患者血压控制不佳,根据研究。应强烈鼓励高血压患者坚持至少三种血液透析治疗,以实现最佳的血压控制。
公众号